Evidence map›Paper›PMID 36359393›Full record

ReviewBiomedicines2022

Therapeutical Targets in Allergic Inflammation.

Lorenzo Salvati, Francesco Liotta, Francesco Annunziato, Lorenzo Cosmi

Abstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Dupilumab treatment and 3-dimensional bronchial tree changes in asthma-COPD overlap.The journal of allergy and clinical immunology. Global · 2025
    Article
  3. Article
  4. CD4 T-Cell Subsets and the Pathophysiology of Inflammatory Bowel Disease.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lorenzo SalvatiDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Firenze, Italy.ORCID 0000-0001-5831-0392
Francesco LiottaDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Firenze, Italy.
Francesco AnnunziatoDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Firenze, Italy.
Lorenzo CosmiDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Firenze, Italy.ORCID 0000-0002-8150-8177

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From the discovery of IgE to the in-depth characterization of Th2 cells and ILC2, allergic inflammation has been extensively addressed to find potential therapeutical targets. To date, omalizumab, an anti-IgE monoclonal antibody, and dupilumab, an anti-IL-4 receptor α monoclonal antibody, represent two pillars of biologic therapy of allergic inflammation. Their increasing indications and long-term follow-up studies are shaping the many different faces of allergy. At the same time, their limitations are showing the intricate pathogenesis of allergic diseases.

Indexed as

allergyasthmaatopic dermatitisCRSwNPdesensitizationdupilumabefficacyeosinophilic esophagitisimmunotherapyomalizumabpractical approachsafetyurticaria

Identifiers

PMID36359393
PMCPMC9687898

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.