Evidence map›Paper›PMID 36360409›Full record

ArticleChildren (Basel, Switzerland)2022

The Absence of Permanent Sensorineural Hearing Loss in a Cohort of Children with SARS-CoV-2 Infection and the Importance of Performing the Audiological "Work-Up".

Rita Malesci, Davide Rizzo, Valeria Del Vecchio, Nicola Serra, Giuseppe Tarallo, Domenico D'Errico, Valentina Coronella, Francesco Bussu, Andrea Lo Vecchio, Gennaro Auletta and 2 more

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Late-onset, progressive sensorineural hearing loss in the paediatric population: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Rita MalesciSection of Audiology, Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy.ORCID 0000-0003-2728-339X
Davide RizzoOtolaryngology Division, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Viale San Pietro, 43, 07100 Sassari, Italy.ORCID 0000-0003-1830-3731
Valeria Del VecchioSection of Audiology, Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy.ORCID 0000-0003-0614-7583
Nicola SerraDepartment of Public Health, University of Naples Federico II, Via Pansini, 5, 80138 Naples, Italy.ORCID 0000-0001-8086-6362
Giuseppe TaralloSection of Audiology, Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy.
Domenico D'ErricoSection of Audiology, Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy.
Valentina CoronellaSection of Audiology, Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy.
Francesco BussuOtolaryngology Division, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Viale San Pietro, 43, 07100 Sassari, Italy.ORCID 0000-0001-6261-2772
Andrea Lo VecchioSection of Pediatrics, Department of Translational Medical Sciences, University of Naples Federico II, Via Pansini, 5, 80138 Naples, Italy.ORCID 0000-0003-4181-6842
Gennaro AulettaSection of Audiology, Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy.ORCID 0000-0003-1548-7141
Annamaria FranzèSection of Audiology, Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy.ORCID 0000-0002-4392-9739
Anna Rita FetoniSection of Audiology, Department of Neuroscience, Reproductive Sciences and Dentistry, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy.
University of Naples Federico II · ITUniversity of Sassari · ITFederico II University Hospital · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrently, the novel coronavirus (SARS-CoV-2) causes an acute respiratory illness named COVID-19 and is a controversial risk factor for hearing loss (HL). Herein, we aim to describe the associated symptoms and to evaluate hearing function in the COVID-19 pediatric population.

methodsA retrospective cross-sectional observational study was carried out on 37 children who contracted COVID-19 infection with no previous audio-vestibular disorders. Clinical data on the infections were collected, and an audiological assessment of all affected children was performed by using different diagnostic protocols according to their age.

resultsFever, upper respiratory and gastrointestinal manifestations were common presentations of infection. Audiological function was normal in 30 (81.08%) children, while 7 children showed an increased hearing threshold: 6 (16.21%) had transient conductive hearing loss (CHL) due to middle ear effusion and normalized at the follow-up and 1 had sensorineural hearing loss (SNHL). A single child was affected by bilateral SNHL (2.7%); however, he underwent a complete audiological work-up leading to a diagnosis of genetic HL due to a MYO6 gene mutation which is causative of progressive or late onset SNHL.

conclusionsHL needs to be considered among the manifestations of COVID-19 in children, nevertheless, we found cases of transient CHL. The onset of HL during or following COVID-19 infection does not eliminate the indication for maintaining audiological surveillance and audiological work-ups, including genetic diagnosis, to avoid the risk of mistaking other causes of HL.

Indexed as

audiological surveillancechildrenCOVID-19genetic hearing losspermanent hearing impairmentSARS-CoV-2

Identifiers

PMID36360409
PMCPMC9689077
OpenAlexW4307923469

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.