Evidence mapPaperPMID 36360559Full record

ArticleHealthcare (Basel, Switzerland)2022

Impact of Multiple Sclerosis and Its Association with Depression: An Analytical Case-Control Investigation.

Francisco Javier Ruiz-Sánchez, Maria do Rosário Martins, Salete Soares, Carlos Romero-Morales, Daniel López-López, Juan Gómez-Salgado, Ana María Jiménez-Cebrián

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Effects of depression on patients suffering from ankylosing spondylitis: a comparative study.Sao Paulo medical journal = Revista paulista de medicina · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francisco Javier Ruiz-SánchezResearch, Health and Podiatry Group, Department of Health Sciences, Faculty of Nursing and Podiatry, Industrial Campus of Ferrol, Universidade da Coruña, 15403 Ferrol, Spain.ORCID 0000-0001-6399-6050
Maria do Rosário MartinsUICISA:E, Escola Superior de Saúde, Instituto Politécnico de Viana do Castelo, Rua D. Moisés Alves Pinho 190, 4900-314 Viana do Castelo, Portugal.ORCID 0000-0002-8609-5834
Salete SoaresUICISA:E, Escola Superior de Saúde, Instituto Politécnico de Viana do Castelo, Rua D. Moisés Alves Pinho 190, 4900-314 Viana do Castelo, Portugal.ORCID 0000-0003-3582-044X
Carlos Romero-MoralesFaculty of Sport Sciences, Universidad Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain.ORCID 0000-0001-6598-829X
Daniel López-LópezResearch, Health and Podiatry Group, Department of Health Sciences, Faculty of Nursing and Podiatry, Industrial Campus of Ferrol, Universidade da Coruña, 15403 Ferrol, Spain.
Juan Gómez-SalgadoDepartment of Sociology, Social Work and Public Health, Faculty of Labor Sciences. University of Huelva, 21007 Huelva, Spain.ORCID 0000-0001-9053-7730
Ana María Jiménez-CebriánNursing and Podiatry Department, Faculty of Health Sciences, Instituto de Investigación Biomédica de Málaga (IBIMA), University of Malaga, 29071 Malaga, Spain.ORCID 0000-0002-8634-7114

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) is a neurological, chronic, inflammatory, and progressive disease with musculoskeletal problems and neurodegenerative disorders that causes worsening of the health status of patients. The aim of this study was to determine the level of depression in MS patients compared to a population of healthy subjects. The established sample size was 116 subjects matched with the same age, sex, and body mass index. The subjects were recruited from different multiple sclerosis associations and neurology clinics in different public health areas (case group n = 58) and healthy subjects from the same locality (control group n = 58). The scores and categories of the Beck Depression Inventory (BDI) in its Spanish version were collected. There was a clear statistically significant difference (p < 0.05) in the BDI scores between both groups. As a result, we found that the subjects with MS presented worse results with BDI = 9.52 ± 7.70 points compared to the healthy subjects with a BDI score = 5.03 ± 5.14. Within the BDI categories, there were statistically significant differences (p < 0.001), which were greater for the MS group. Depression is a dangerous factor for MS patients, being a trigger for a poorer quality of life.

Indexed as

Beck depression inventorydepressionmultiple sclerosis

Identifiers

PMID36360559
PMCPMC9690715

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.