Evidence map›Paper›PMID 36362113›Full record

ArticleInternational journal of molecular sciences2022

Protective Role of Hepassocin against Hepatic Endoplasmic Reticulum Stress in Mice.

Yang Yang, Hui Chen, Yue Wan, Diandian Dong, Xiaofang Wang, Songhui Yao, Pengjun Wang, Shensi Xiang, Xiaoming Yang, Miao Yu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
  4. Ablation of Hepatocyte Derived-FGL1 Does Not Aggravate Metabolic Dysfunction-Associated Steatotic Liver Disease.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  5. ER CaCell & bioscience · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yang YangDepartment of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Hui ChenBeijing Institute of Radiation Medicine, Beijing 100850, China.
Yue WanBeijing Institute of Radiation Medicine, Beijing 100850, China.
Diandian DongBeijing Institute of Radiation Medicine, Beijing 100850, China.
Xiaofang WangBeijing Institute of Radiation Medicine, Beijing 100850, China.
Songhui YaoBeijing Institute of Radiation Medicine, Beijing 100850, China.
Pengjun WangState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Institute of Lifeomics, Beijing 102206, China.
Shensi XiangBeijing Institute of Radiation Medicine, Beijing 100850, China.
Xiaoming YangDepartment of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Miao YuBeijing Institute of Radiation Medicine, Beijing 100850, China.
Beijing Radiation Center · CNAnhui Medical University · CNBeijing Proteome Research Center · CNTianjin University · CN

Funding

National Natural Science Foundation of China 82070596Natural Science Foundation of Beijing of China 7182124the State Key Laboratory of Proteomics SKLP-K201404
6 · The paper itself

Abstract

Hepassocin (HPS) is a hepatokine that has multiple proposed physiological functions. Some of the biological processes in which it is involved are closely related to endoplasmic reticulum (ER) stress, but the role of HPS in the regulation of ER stress remains unclear. Here, we demonstrated that

Indexed as

Endoplasmic Reticulum StressFatty LiverAnimalsCalciumHepatocytesLiverMiceMice, Inbred C57BLTunicamycinCalciumTunicamycinER stresshepassocinlipid accumulationliver injury

Identifiers

PMID36362113
PMCPMC9658083
OpenAlexW4308118973

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.