Evidence map›Paper›PMID 36362116›Full record

ArticleInternational journal of molecular sciences2022

Chemokine Profile in Psoriasis Patients in Correlation with Disease Severity and Pruritus.

Dorota Purzycka-Bohdan, Bogusław Nedoszytko, Monika Zabłotna, Jolanta Gleń, Aneta Szczerkowska-Dobosz, Roman J Nowicki

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Harnessing Quinone Derivatives fromACS pharmacology & translational science · 2025
    Article
  8. Review
  9. Exploring Pruritus in Bullous Pemphigoid: Analysis of QOL Metrics and Potential Biological Mechanisms.JID innovations : skin science from molecules to population health · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Nanophytosomal Gel ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  15. Review
  16. Dermal Delivery ofRecent advances in drug delivery and formulation · 2024
    Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dorota Purzycka-BohdanDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0002-6089-8030
Bogusław NedoszytkoDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0002-6286-0693
Monika ZabłotnaDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.
Jolanta GleńDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.
Aneta Szczerkowska-DoboszDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.
Roman J NowickiDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0003-4768-1387

Funding

The research was supported by funds from the Polish Ministry of Science and Higher Education 02- 0066/07/253
6 · The paper itself

Abstract

Psoriasis (PsO) is a chronic, immune-mediated, inflammatory skin disease associated in most cases with pruritus. Chemokines seem to play a significant role in PsO pathogenesis. The aim of the study was to analyse serum concentrations of CCL2/MCP-1, CCL3/MIP-1α, CCL4/MIP-1β, CCL5/RANTES, CCL17/TARC, CCL18/PARC, CCL22/MDC and CXCL8/IL-8, and their correlation with PsO severity and pruritus intensity. The study included 60 PsO patients and 40 healthy volunteers. Serum concentrations of six (CCL2/MCP-1, CCL3/MIP-1α, CCL5/RANTES, CCL17/TARC, CCL18/PARC and CCL22/MDC) out of eight analysed chemokines were significantly elevated in PsO patients; however, they did not correlate with disease severity. The serum level of CCL5/RANTES was significantly higher in patients with the psoriasis area and severity index (PASI) ≥ 15 (

Indexed as

Chemokine CCL5PsoriasisChemokine CCL2Chemokine CCL3ChemokinesHumansPruritusSeverity of Illness IndexChemokine CCL2Chemokine CCL3Chemokine CCL5Chemokineschemokinesdisease severityprurituspsoriasis

Identifiers

PMID36362116
PMCPMC9655759

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.