Evidence map›Paper›PMID 36362179›Full record

ArticleInternational journal of molecular sciences2022

Therapeutic Ultrasound Halts Progression of Chronic Kidney Disease In Vivo via the Regulation of Markers Associated with Renal Epithelial-Mesenchymal Transition and Senescence.

Chen-Yu Lin, Ching-Chia Wang, Jui-Zhi Loh, Tsai-Chen Chiang, Te-I Weng, Ding-Cheng Chan, Kuan-Yu Hung, Chih-Kang Chiang, Shing-Hwa Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chen-Yu LinInstitute of Toxicology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Ching-Chia WangDepartment of Pediatrics, National Taiwan University Hospital, Taipei 100, Taiwan.
Jui-Zhi LohInstitute of Toxicology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Tsai-Chen ChiangInstitute of Toxicology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Te-I WengDepartment of Forensic Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Ding-Cheng ChanDepartment of Geriatrics and Gerontology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Kuan-Yu HungDepartment of Internal Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Chih-Kang ChiangInstitute of Toxicology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.ORCID 0000-0001-9021-4616
Shing-Hwa LiuInstitute of Toxicology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.ORCID 0000-0002-9976-1197
National Taiwan University · TWNational Taiwan University Hospital · TW

Funding

Ministry of Science and Technology of Taiwan MOST105-2314-B-002-106-MY3; MOST108-2314-B-002-070-MY3the National Science and Technology of Council of Taiwan NSTC111-2314-B-002-233
6 · The paper itself

Abstract

Low-intensity pulsed ultrasound (LIPUS), a therapeutic type of ultrasound, is known to enhance bone fracture repair processes and help some tissues to heal. Here, we investigated the therapeutic potential of LIPUS for the treatment of chronic kidney disease (CKD) in two CKD mouse models. CKD mice were induced using both unilateral renal ischemia/reperfusion injury (IRI) with nephrectomy and adenine administration. The left kidneys of the CKD mice were treated using LIPUS with the parameters of 3 MHz, 100 mW/cm

Indexed as

Epithelial-Mesenchymal TransitionRenal Insufficiency, ChronicAdenineAnimalsBiomarkersFibrosisKidneyMiceAdenineBiomarkerschronic kidney diseaserenal injurysenescencetherapeutic ultrasound

Identifiers

PMID36362179
PMCPMC9654276
OpenAlexW4307995075

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.