Evidence map›Paper›PMID 36362467›Full record

ArticleJournal of clinical medicine2022

Neuromuscular Electrical Stimulation during Hemodialysis Suppresses Postprandial Hyperglycemia in Patients with End-Stage Diabetic Kidney Disease: A Crossover Controlled Trial.

Tomoki Tsurumi, Yuma Tamura, Yuki Nakatani, Tomoki Furuya, Hajime Tamiya, Masato Terashima, Takashi Tomoe, Asuka Ueno, Masahiro Shimoyama, Takanori Yasu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tomoki TsurumiDepartment of Rehabilitation, Dokkyo Medical University Nikko Medical Center, Nikko 321-2593, Japan.
Yuma TamuraDepartment of Rehabilitation, Dokkyo Medical University Nikko Medical Center, Nikko 321-2593, Japan.ORCID 0000-0002-6439-3515
Yuki NakataniDepartment of Diabetes and Endocrinology, Dokkyo Medical University Nikko Medical Center, Nikko 321-2593, Japan.
Tomoki FuruyaDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko 321-2593, Japan.
Hajime TamiyaDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko 321-2593, Japan.
Masato TerashimaDepartment of Rehabilitation, Dokkyo Medical University Nikko Medical Center, Nikko 321-2593, Japan.
Takashi TomoeDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko 321-2593, Japan.
Asuka UenoDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko 321-2593, Japan.
Masahiro ShimoyamaDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko 321-2593, Japan.
Takanori YasuDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University Nikko Medical Center, Nikko 321-2593, Japan.ORCID 0000-0002-1940-2347
Dokkyo Medical University · JPNiigata University of Health and Welfare · JPTokyo Metropolitan Institute of Gerontology · JP

Funding

Dokkyo Medical University 2021-24Japan Society for the Promotion of Science 17K18050
6 · The paper itself

Abstract

Hemodialysis patients with diabetic kidney disease (DKD) experience blood glucose fluctuations owing to insulin removal. We evaluated the effects of single and long-term application of neuromuscular electrical stimulation (NMES) during hemodialysis on glycemic control. This trial was conducted in two stages: Stage 1, following a crossover design and 4 week washout period, eleven outpatients with DKD either underwent a single bout of NMES for 30 min (NMES period) or rested (control period) after receiving nutritional support during hemodialysis; Stage 2, following a crossover design and 4 week washout period, each participant received the intervention for 12 weeks. NMES was administered for 30 min at the maximum tolerable intensity. The mean subcutaneous glucose concentration and mean amplitude of glycemic excursion (MAGE) were determined by flash glucose monitoring for 24 h. Changes in glycoalbumin and MAGE before and after NMES initiation were evaluated. The mean blood glucose level and MAGE after a single bout of NMES were significantly lower than those after rest. Glycoalbumin levels and echo intensity of the rectus femoris tended to decrease, but not significantly by ANOVA due to a lack in statistical power after the dropout of three patients. NMES in end-stage DKD decreased blood glucose levels during and after hemodialysis.

Indexed as

diabetic kidney diseaseglycemic controlhemodialysisneuromuscular electrical stimulation

Identifiers

PMID36362467
PMCPMC9658571
OpenAlexW4307265311

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.