Evidence map›Paper›PMID 36364321›Full record

ArticleMolecules (Basel, Switzerland)2022

Inhibitory Effect of Isoliquiritigenin in Niemann-Pick C1-Like 1-Mediated Cholesterol Uptake.

Jun Zeng, Wenjing Liu, Bing Liang, Lingyu Shi, Shanbo Yang, Jingsen Meng, Jing Chang, Xiaokun Hu, Renshuai Zhang, Dongming Xing

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  3. Article
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  6. Review
  7. Natural Chalcones for the Management of Obesity Disease.International journal of molecular sciences · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jun ZengCancer Institute, The Affiliated Hospital of Qingdao University, School of Basic Medicine of Qingdao University, Qingdao 266000, China.
Wenjing LiuCancer Institute, The Affiliated Hospital of Qingdao University, School of Basic Medicine of Qingdao University, Qingdao 266000, China.
Bing LiangCancer Institute, The Affiliated Hospital of Qingdao University, School of Basic Medicine of Qingdao University, Qingdao 266000, China.
Lingyu ShiCancer Institute, The Affiliated Hospital of Qingdao University, School of Basic Medicine of Qingdao University, Qingdao 266000, China.
Shanbo YangCancer Institute, The Affiliated Hospital of Qingdao University, School of Basic Medicine of Qingdao University, Qingdao 266000, China.
Jingsen MengCancer Institute, The Affiliated Hospital of Qingdao University, School of Basic Medicine of Qingdao University, Qingdao 266000, China.
Jing ChangCancer Institute, The Affiliated Hospital of Qingdao University, School of Basic Medicine of Qingdao University, Qingdao 266000, China.
Xiaokun HuDepartment of Neurosurgery, The Affiliated Hospital of Qingdao University, Qingdao 266000, China.
Renshuai ZhangQingdao Cancer Institute, Qingdao 266000, China.
Dongming XingQingdao Cancer Institute, Qingdao 266000, China.
Affiliated Hospital of Qingdao University · CNQingdao University · CNTsinghua University · CN

Funding

the Natural Science Foundation of Shandong Province ZR2021QH212, ZR2020MH369the Youth Innovation Team Talent Introduction Program of Shandong Province 20190164
6 · The paper itself

Abstract

Isoliquiritigenin (ISL) is a flavonoid with a chalcone structure extracted from the natural herb

Indexed as

Anticholesteremic AgentsChalconesBiological TransportCholesterolMembrane Transport ProteinsAnticholesteremic AgentsChalconesCholesterolisoliquiritigeninMembrane Transport Proteinscardiovascular diseasecholesterol uptakeinhibitorsisoliquiritigeninNiemann-Pick C1-Like 1 (NPC1L1)

Identifiers

PMID36364321
PMCPMC9654431
OpenAlexW4309090708

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.