Evidence map›Paper›PMID 36364353›Full record

ArticleMolecules (Basel, Switzerland)2022

Propolis Efficacy: The Quest for Eco-Friendly Solvents.

Ana Sofia Freitas, Ana Cunha, Pier Parpot, Susana M Cardoso, Rui Oliveira, Cristina Almeida-Aguiar

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ana Sofia FreitasCITAB-Centre for the Research and Technology of Agro-Environmental and Biological Sciences, University of Minho, 4710-057 Braga, Portugal.
Ana CunhaDepartment of Biology, School of Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0003-0822-8248
Pier ParpotCQUM-Chemistry Center of the University of Minho, Department of Chemistry, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Susana M CardosoLAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-7882-737X
Rui OliveiraDepartment of Biology, School of Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-3989-8925
Cristina Almeida-AguiarDepartment of Biology, School of Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0001-8223-8634
University of Minho · PTRede de Química e Tecnologia · PT

Funding

Fundação para a Ciência e Tecnologia CITAB research unit (UIDB/04033/2020), CBMA research unit (Contrato-Programa UIDB/04050/2020), Centre of Chemistry (UID/QUI/0686/2016)Fundação para a Ciência e Tecnologia PD/00122/2012Fundação para a Ciência e Tecnologia PD/BD/128276/2017
6 · The paper itself

Abstract

Propolis, a natural product made by bees with resins and balsams, is known for its complex chemical composition and remarkable bioactivities. In this study, propolis extraction was studied seeking extracts with strong bioactivities using less orthodox solvents, with some derived from apiary products. For that, a propolis sample collected from Gerês apiary in 2018 (G18) was extracted by maceration with six different solvents: absolute ethanol, ethanol/water (7:3), honey brandy, mead, propylene glycol and water. The solvent influence on the chemical composition and antioxidant and antimicrobial activities of the extracts was investigated. Antioxidant potential was assessed by the DPPH free-radical-scavenging assay and the antimicrobial activity by the agar dilution method. Chemical composition of the extracts was determined in vitro by three colorimetric assays: total ortho-diphenols, phenolics and flavonoids contents and the LC-MS technique. To our knowledge, this is the first time that solvents such as honey brandy and mead have been studied. Honey brandy showed considerable potential to extract propolis active compounds able to inhibit the growth of bacteria such as the methicillin-sensitive

Indexed as

Anti-Infective AgentsMethicillin-Resistant Staphylococcus aureusPropolisAntioxidantsCandida albicansEscherichia coliEthanolMicrobial Sensitivity TestsSolventsWaterAnti-Infective AgentsAntioxidantsEthanolPropolisSolventsWaterantibacterial activityantioxidant potentialphenolic compoundspropolispropolis extractionpropolis extraction solvents

Identifiers

PMID36364353
PMCPMC9655633
OpenAlexW4308351984

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.