Evidence map›Paper›PMID 36364354›Full record

ReviewMolecules (Basel, Switzerland)2022

Recent Advances in Herbal-Derived Products with Skin Anti-Aging Properties and Cosmetic Applications.

Erika F Costa, Wagner V Magalhães, Luiz C Di Stasi

Registry-linked trialAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05734703 (Skin Rejuvenation Using Topical Hemp-based Extract and Other Nutraceuticals), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05734703 early_phase1unknown statusnot on this mapstarted 2023, after this paper: background citation

Skin Rejuvenation Using Topical Hemp-based Extract and Other Nutraceuticals

TypeinterventionalSponsorMedical Life Care Planners, LLCRan2023 to 2023Enrolled25ConditionsWrinkle, Spot Pigmented, Lines SkinArmsNutraceutical Topical
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Bioactive materials · 2026
    Article
  4. Article
  5. Antioxidants (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Article
  8. Potential Cosmetic Applications of Dihydroartemisinin.Molecules (Basel, Switzerland) · 2026
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Multifunctional Dermatological Effects of Whole-PlantCurrent issues in molecular biology · 2025
    Article
  16. Article
  17. Harnessing the Power ofMolecules (Basel, Switzerland) · 2025
    Review
  18. Crystal structure, Hirshfeld surface, DFT, mol-ecular docking of 1-[(6-Acta crystallographica. Section E, Crystallographic communications · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Erika F CostaLaboratory of Phytomedicines, Pharmacology, and Biotechnology (PhytoPharmaTech), Department of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu 18618-689, SP, Brazil.ORCID 0000-0003-2984-3960
Wagner V MagalhãesResearch and Development Department, Chemyunion Ltd., Sorocaba 18087-101, SP, Brazil.ORCID 0000-0003-4530-2785
Luiz C Di StasiLaboratory of Phytomedicines, Pharmacology, and Biotechnology (PhytoPharmaTech), Department of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu 18618-689, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although aesthetic benefits are a desirable effect of the treatment of skin aging, it is also important in controlling several skin diseases, mainly in aged people. The development of new dermocosmetics has rapidly increased due to consumers' demand for non-invasive products with lower adverse effects than those currently available on the market. Natural compounds of plant origin and herbal-derived formulations have been popularized due to their various safe active products, which act through different mechanisms of action on several signaling pathways for skin aging. Based on this, the aim of the review was to identify the recent advances in herbal-derived product research, including herbal formulations and isolated compounds with skin anti-aging properties. The studies evaluated the biological effects of herbal-derived products in in vitro, ex vivo, and in vivo studies, highlighting the effects that were reported in clinical trials with available pharmacodynamics data that support their protective effects to treat, prevent, or control human skin aging. Thus, it was possible to identify that gallic and ferulic acids and herbal formulations containing

Indexed as

CosmeticsSkin AgingAgedAgingAntioxidantsHumansPlant ExtractsSkinAntioxidantsCosmeticsPlant Extractscosmeticherbal formulationsnatural productsskin anti-aging

Identifiers

PMID36364354
PMCPMC9658815

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.