Evidence map›Paper›PMID 36364369›Full record

ArticleMolecules (Basel, Switzerland)2022

Pyridine Carboxamides Based on Sulfobetaines: Design, Reactivity, and Biological Activity.

Eugene P Kramarova, Sophia S Borisevich, Edward M Khamitov, Alexander A Korlyukov, Pavel V Dorovatovskii, Anastasia D Shagina, Konstantin S Mineev, Dmitri V Tarasenko, Roman A Novikov, Alexey A Lagunin and 6 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Eugene P KramarovaDepartment of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.
Sophia S BorisevichLaboratory of Physical Chemistry, Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 450071 Ufa, Russia.ORCID 0000-0001-8481-0470
Edward M KhamitovLaboratory of Physical Chemistry, Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 450071 Ufa, Russia.ORCID 0000-0001-8987-4254
Alexander A KorlyukovDepartment of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0002-5600-9886
Pavel V DorovatovskiiNational Research Center "Kurchatov Institute", 123098 Moscow, Russia.
Anastasia D ShaginaDepartment of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.
Konstantin S MineevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-2418-9421
Dmitri V TarasenkoDepartment of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.
Roman A NovikovN.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russia.
Alexey A LaguninDepartment of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0003-1757-8004
Ivan BoldyrevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-5683-0295
Aiarpi A EzdoglianDepartment of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.
Natalia Yu KarpechenkoDepartment of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0002-5902-0378
Tatiana A ShmigolDepartment of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0002-5195-0845
Yuri I BaukovDepartment of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.
Vadim V NegrebetskyDepartment of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0001-6852-8942
Pirogov Russian National Research Medical University · RUInstitute of Bioorganic Chemistry · RUUfa Institute of Chemistry · RUKurchatov Institute · RUN.D. Zelinsky Institute of Organic Chemistry · RU

Funding

Russian Foundation of Basic Research 20-03-00858Russian Science Foundation 21-73-20250
6 · The paper itself

Abstract

The synthesis of the products of the 1,3-propanesultone ring opening during its interaction with amides of pyridinecarboxylic acids has been carried out. The dependence of the yield of the reaction products on the position (

Indexed as

AmidesPyridinesAlkylationBetaineAmidesBetainePyridinessulfobetainederivatives of pyridine carboxylic acidsmechanism of reactionNMR and FT-IR spectroscopyquantum-chemical calculationssulfobetainesX-ray

Identifiers

PMID36364369
PMCPMC9658115
OpenAlexW4308333220

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.