Evidence map›Paper›PMID 36364651›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Encapsulation of Luminescent Gold Nanoclusters into Synthetic Vesicles.

Regina M Chiechio, Solène Ducarre, Célia Marets, Aurélien Dupont, Pascale Even-Hernandez, Xavier Pinson, Stéphanie Dutertre, Franck Artzner, Paolo Musumeci, Célia Ravel and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Regina M ChiechioInstitut des Sciences Chimiques de Rennes, CNRS UMR 6226, Université Rennes 1, F-35000 Rennes, France.ORCID 0000-0002-6469-3059
Solène DucarreIMM-CNR, Via S. Sofia 64, 95123 Catania, Italy.
Célia MaretsInstitut des Sciences Chimiques de Rennes, CNRS UMR 6226, Université Rennes 1, F-35000 Rennes, France.ORCID 0000-0002-5670-1020
Aurélien DupontBIOSIT, Inserm, CNRS UMS 3480, Université Rennes1, US_S 018, F-35000 Rennes, France.
Pascale Even-HernandezInstitut des Sciences Chimiques de Rennes, CNRS UMR 6226, Université Rennes 1, F-35000 Rennes, France.ORCID 0000-0002-2187-1150
Xavier PinsonMicroscopy Rennes Imaging Centre, SFR Biosit, CNRS UMS 3480-US INSERM 018, Université Rennes 1, F-35000 Rennes, France.
Stéphanie DutertreMicroscopy Rennes Imaging Centre, SFR Biosit, CNRS UMS 3480-US INSERM 018, Université Rennes 1, F-35000 Rennes, France.
Franck ArtznerInstitut de Physique, CNRS UMR 6251, Université Rennes 1, F-35000 Rennes, France.ORCID 0000-0002-5613-576X
Paolo MusumeciDipartimento di Fisica e Astronomia "Ettore Majorana", Università Di Catania, Via Santa Sofia 64, 95123 Catania, Italy.
Célia RavelService de Biologie de la Reproduction-CECOS, CHU Rennes, F-35000 Rennes, France.
Maria Jose Lo FaroDipartimento di Fisica e Astronomia "Ettore Majorana", Università Di Catania, Via Santa Sofia 64, 95123 Catania, Italy.ORCID 0000-0002-2067-1608
Valérie MarchiInstitut des Sciences Chimiques de Rennes, CNRS UMR 6226, Université Rennes 1, F-35000 Rennes, France.ORCID 0000-0002-6565-7201
Centre National de la Recherche Scientifique · FRUniversity of Catania · ITInserm · FRInstitute for Microelectronics and Microsystems · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold nanoclusters (Au NCs) are attractive luminescent nanoprobes for biomedical applications. In vivo biosensing and bioimaging requires the delivery of the Au NCs into subcellular compartments. In this view, we explore here the possible encapsulation of ultra-small-sized red and blue emitting Au NCs into liposomes of various sizes and chemical compositions. Different methods were investigated to prepare vesicles containing Au NCs in their lumen. The efficiency of the process was correlated to the structural and morphological aspect of the Au NCs' encapsulating vesicles thanks to complementary analyses by SAXS, cryo-TEM, and confocal microscopy techniques. Cell-like-sized vesicles (GUVs) encapsulating red or blue Au NCs were successfully obtained by an innovative method using emulsion phase transfer. Furthermore, exosome-like-sized vesicles (LUVs) containing Au NCs were obtained with an encapsulation yield of 40%, as estimated from ICP-MS.

Indexed as

encapsulationgold nanoclustersvesicles

Identifiers

PMID36364651
PMCPMC9655092
OpenAlexW4308774123

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.