Evidence map›Paper›PMID 36364899›Full record

ReviewNutrients2022

A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges.

Vivek Puri, Manju Nagpal, Inderbir Singh, Manjinder Singh, Gitika Arora Dhingra, Kampanart Huanbutta, Divya Dheer, Ameya Sharma, Tanikan Sangnim

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  8. Polysaccharides and carbohydrate polymers: innovations from nature to industry.Journal of the science of food and agriculture · 2026
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vivek PuriSchool of Pharmacy, Chitkara University, Baddi 174103, Himachal Pradesh, India.ORCID 0000-0002-4497-9412
Manju NagpalCollege of Pharmacy, Chitkara University, Rajpura 140401, Punjab, India.
Inderbir SinghCollege of Pharmacy, Chitkara University, Rajpura 140401, Punjab, India.ORCID 0000-0002-1860-4246
Manjinder SinghCollege of Pharmacy, Chitkara University, Rajpura 140401, Punjab, India.
Gitika Arora DhingraNCRD's Sterling Institute of Pharmacy, Nerul, Navi Mumbai 400706, Maharashtra, India.
Kampanart HuanbuttaSchool of Pharmacy, Eastern Asia University, Pathum Thani 12110, Tanyaburi, Thailand.ORCID 0000-0001-8188-153X
Divya DheerSchool of Pharmacy, Chitkara University, Baddi 174103, Himachal Pradesh, India.
Ameya SharmaSchool of Pharmacy, Chitkara University, Baddi 174103, Himachal Pradesh, India.ORCID 0000-0003-3810-4238
Tanikan SangnimFaculty of Pharmaceutical Sciences, Burapha University, Chonburi 20131, Muang, Thailand.ORCID 0000-0002-9332-384X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutraceuticals are the nourishing components (hybrid of nutrition and pharmaceuticals) that are biologically active and possess capability for maintaining optimal health and benefits. These products play a significant role in human health care and its endurance, most importantly for the future therapeutic development. Nutraceuticals have received recognition due to their nutritional benefits along with therapeutic effects and safety profile. Nutraceuticals are globally growing in the field of services such as health care promotion, disease reduction, etc. Various drug nutraceutical interactions have also been elaborated with various examples in this review. Several patents on nutraceuticals in agricultural applications and in various diseases have been stated in the last section of review, which confirms the exponential growth of nutraceuticals' market value. Nutraceuticals have been used not only for nutrition but also as a support therapy for the prevention and treatment of various diseases, such as to reduce side effects of cancer chemotherapy and radiotherapy. Diverse novel nanoformulation approaches tend to overcome challenges involved in formulation development of nutraceuticals. Prior information on various interactions with drugs may help in preventing any deleterious effects of nutraceuticals products. Nanotechnology also leads to the generation of micronized dietary products and other nutraceutical supplements with improved health benefits. In this review article, the latest key findings (clinical studies) on nutraceuticals that show the therapeutic action of nutraceutical's bioactive molecules on various diseases have also been discussed.

Indexed as

Dietary SupplementsNutritional StatusHumanscardiovascular diseasesinteractionsnutritionpreventiontherapeutics

Identifiers

PMID36364899
PMCPMC9654660

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.