Evidence mapPaperPMID 36364943Full record

ReviewNutrients2022

The Role of Catechins in Regulating Diabetes: An Update Review.

Lianghua Wen, Dan Wu, Xindong Tan, Meiqi Zhong, Jiabao Xing, Wei Li, Dan Li, Fanrong Cao

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Bioactivities ofInternational journal of molecular sciences · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Exploring the Antidiabetic Properties ofMolecules (Basel, Switzerland) · 2025
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Dual effects ofNarra J · 2025
    Article
  18. Antidiabetic Effects and Mechanisms of Action of Uncaria gambir Roxb. in Diabetic Sprague-Dawley Rats.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  19. Emerging Role ofMini reviews in medicinal chemistry · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lianghua WenCollege of Horticulture, South China Agricultural University, Guangzhou 510640, China.
Dan WuCollege of Horticulture, South China Agricultural University, Guangzhou 510640, China.ORCID 0000-0001-8041-4016
Xindong TanCollege of Horticulture, South China Agricultural University, Guangzhou 510640, China.
Meiqi ZhongCollege of Horticulture, South China Agricultural University, Guangzhou 510640, China.
Jiabao XingCollege of Horticulture, South China Agricultural University, Guangzhou 510640, China.
Wei LiCollege of Horticulture, South China Agricultural University, Guangzhou 510640, China.
Dan LiCollege of Horticulture, South China Agricultural University, Guangzhou 510640, China.
Fanrong CaoCollege of Horticulture, South China Agricultural University, Guangzhou 510640, China.
South China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Catechins are key functional components in tea and have many health benefits, including relieving diabetes. Glucose is necessary for maintaining life. However, when the glucose in the serum exceeds the threshold, it will lead to hyperglycemia. Hyperglycemia is mainly caused by insufficient insulin secretion or insulin resistance. Persistent hyperglycemia can cause various disorders, including retinopathy, nephropathy, neurodegenerative diseases, cardiovascular disease, and diabetes. In this paper, we summarize the research on the underlying mechanisms of catechins in regulating diabetes and elaborate on the mechanisms of catechins in alleviating hyperglycemia by improving insulin resistance, alleviating oxidative stress, regulating mitochondrial function, alleviating endoplasmic reticulum stress, producing anti-inflammatory effects, reducing blood sugar source, and regulating intestinal function. This review will provide scientific direction for future research on catechin alleviating diabetes.

Indexed as

CatechinDiabetes MellitusHyperglycemiaInsulin ResistanceGlucoseHumansTeaCatechinGlucoseTeaguthyperglycemiainsulin resistancemitochondrial damageoxidative stresstea

Identifiers

PMID36364943
PMCPMC9654920
OpenAlexW4308441609

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.