Evidence mapPaperPMID 36364954Full record

ReviewNutrients2022

The Effect of Healthy Lifestyle Strategies on the Management of Insulin Resistance in Children and Adolescents with Obesity: A Narrative Review.

Valeria Calcaterra, Elvira Verduci, Matteo Vandoni, Virginia Rossi, Giulia Fiore, Giulia Massini, Clarissa Berardo, Alessandro Gatti, Paola Baldassarre, Alice Bianchi and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  7. Preventing Metabolic Syndrome in Adolescents Through Exercise.Advances in experimental medicine and biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Valeria CalcaterraPediatric and Adolescent Unit, Department of Internal Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-2137-5974
Elvira VerduciPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0003-2111-3111
Matteo VandoniLaboratory of Adapted Motor Activity (LAMA), Department of Public Health, Experimental Medicine and Forensic Science, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-3405-9364
Virginia RossiPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0001-8363-9210
Giulia FiorePediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0002-6100-5687
Giulia MassiniPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Clarissa BerardoDepartment of Biomedical and Clinical Science, University of Milano, 20157 Milan, Italy.ORCID 0000-0002-1257-5843
Alessandro GattiLaboratory of Adapted Motor Activity (LAMA), Department of Public Health, Experimental Medicine and Forensic Science, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0001-6628-7938
Paola BaldassarrePediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Alice BianchiPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Erika CordaroPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0001-6634-9254
Caterina CavalloLaboratory of Adapted Motor Activity (LAMA), Department of Public Health, Experimental Medicine and Forensic Science, University of Pavia, 27100 Pavia, Italy.
Cristina CeredaNeonatal Screening and Metabolic Disorders Unit, V. Buzzi Children's Hospital, 20154 Milan, Italy.ORCID 0000-0001-9571-0862
Alessandra BosettiPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Gianvincenzo ZuccottiPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0002-2795-9874
Ospedale dei Bambini Vittore Buzzi · ITUniversity of Pavia · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood obesity is characterized by an increased risk of several metabolic derangements including insulin resistance (IR). The strongest recommendations to prevent obesity and related complications are a balanced and adequate diet and practicing physical activity from early childhood. In this review, we propose to present the effects of healthy lifestyle strategies, including physical exercise and dietary approaches, on the management of IR and related metabolic derangements. All types of exercise (aerobic, resistance and combined training) effectively reduce IR in pediatric patients with obesity; it seems that aerobic and combined training stimulate greater improvements in IR compared to resistance training. Balanced normocaloric or hypocaloric dietary approaches are also valid strategies to address IR; it is not possible to assess the long-term impact of varying macronutrients on cardiometabolic risk. The glycemic index/load evaluation is a useful dietary approach to glucose metabolism control. Similarly, they should adopt the principle of the Mediterranean diet. Randomized studies with longer monitoring are needed to define the benefits of nutritional supplementation on IR. Considering that healthy style acquisition could track to later ages, programs of healthy lifestyle starting with children offer a better preventive strategy to preserve metabolic control and children's health.

Indexed as

Insulin ResistancePediatric ObesityAdolescentChildChild, PreschoolExerciseHealthy LifestyleHumansLife Styleadolescentschildrendietexercisehealthy lifestyleinsulin resistancenutritionalobesity

Identifiers

PMID36364954
PMCPMC9657567
OpenAlexW4308441123

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.