Evidence map›Paper›PMID 36367692›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2022

Vasomotor symptoms of menopause, autonomic dysfunction, and cardiovascular disease.

Emma Lee, Miguel Anselmo, Chowdhury Tasnova Tahsin, Marnie Vanden Noven, William Stokes, Jason R Carter, Manda L Keller-Ross

Registry-linked trialAbstract readReview
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07254429 (Copenhagen Menopause Study), which is not on this map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07254429 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

Copenhagen Menopause Study (COMPASS): A Randomized Clinical Trial

TypeinterventionalSponsorMartin Blomberg JensenRan2025 to 2028Enrolled192ConditionsMenopausal Osteoporosis, Bone MarkersArmsTriptorelin 11.25 mg, Sodium Chloride 0.9%, Estradiol (E2), Testosterone, Placebo gel
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review.Cardiovascular & hematological disorders drug targets · 2026
    Pooled it
  4. Trial
  5. Trial
  6. International journal of molecular medicine · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Vasomotor symptoms of menopause, sympathetic activity, and blood pressure in postmenopausal females.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  18. Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emma LeeDivision of Physical Therapy, Medical School, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0001-7033-6632
Miguel AnselmoDivision of Physical Therapy, Medical School, University of Minnesota, Minneapolis, Minnesota.
Chowdhury Tasnova TahsinDivision of Rehabilitation Science, Medical School, University of Minnesota, Minneapolis, Minnesota.
Marnie Vanden NovenDepartment of Exercise Science, Belmont University, Nashville, Tennessee.
William StokesDivision of Rehabilitation Science, Medical School, University of Minnesota, Minneapolis, Minnesota.
Jason R CarterDepartment of Health and Human Development, Montana State University, Bozeman, Montana.ORCID 0000-0001-7350-6537
Manda L Keller-RossDivision of Physical Therapy, Medical School, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0001-9363-5379

Funding

Alcohol and Neurovascular Control in HumansR01AA024892 · NIAAA · MONTANA STATE UNIVERSITY - BOZEMAN · PI CARTER, JASON R · 2017 to 2021
$1.8M
A New Histone H3 Modification Regulates Epigenetic Programming and Gene Expression in Breast CancerR01CA274924 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Qing Zhang · 2023 to 2026
$1.7M
Autonomic regulation of blood pressure in premature and early menopausal womenK01AG064038 · NIA · UNIVERSITY OF MINNESOTA · PI KELLER-ROSS, MANDA LINEA · 2020 to 2024
$647k
Vascular regulation in postmenopausal femalesF32HL160012 · NHLBI · UNIVERSITY OF MINNESOTA · PI LEE, EMMA JEAN · 2022 to 2024
$193k
NCI NIH HHS R01 CA274924NHLBI NIH HHS F32 HL160012NIAAA NIH HHS R01 AA024892NIA NIH HHS K01 AG064038
6 · The paper itself

Abstract

Cardiovascular disease (CVD), the leading cause of death among US adults, is more prevalent in menopausal females compared with age-matched males. Vasomotor symptoms of menopause (VMS; hot flashes/flushes and night sweats) are common among females undergoing menopausal transition and have been associated with elevated blood pressure (BP) and increased CVD risk. Autonomic dysregulation of BP has been posited as a contributing factor to the elevated CVD risk in menopausal females with VMS. This review includes

Indexed as

Autonomic Nervous System DiseasesCardiovascular DiseasesAdultFemaleHot FlashesHumansMenopauseSweatingVasomotor Systemblood pressurehot flushesmenopausenight sweatssex differences

Identifiers

PMID36367692
PMCPMC9744645

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.