Evidence mapPaperPMID 36375584Full record

ReviewNeuroscience and biobehavioral reviews2023

Computational perspectives on human fear and anxiety.

Yumeya Yamamori, Oliver J Robinson

Open access · hybridAbstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Direct modulation of human GABA-A αFrontiers in neuroscience · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Difficult-to-Treat Anxiety: A Neurocomputational Framework.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Yumeya YamamoriInstitute of Cognitive Neuroscience, University College London, UK. Electronic address: yumeya.yamamori@ucl.ac.uk.
Oliver J RobinsonInstitute of Cognitive Neuroscience, University College London, UK; Clinical, Educational and Health Psychology, University College London, UK.
Mental Health Research UK · GBUniversity College London · GB

Funding

Medical Research Council MR/R020817/1Wellcome Trust
6 · The paper itself

Abstract

Fear and anxiety are adaptive emotions that serve important defensive functions, yet in excess, they can be debilitating and lead to poor mental health. Computational modelling of behaviour provides a mechanistic framework for understanding the cognitive and neurobiological bases of fear and anxiety, and has seen increasing interest in the field. In this brief review, we discuss recent developments in the computational modelling of human fear and anxiety. Firstly, we describe various reinforcement learning strategies that humans employ when learning to predict or avoid threat, and how these relate to symptoms of fear and anxiety. Secondly, we discuss initial efforts to explore, through a computational lens, approach-avoidance conflict paradigms that are popular in animal research to measure fear- and anxiety-relevant behaviours. Finally, we discuss negative biases in decision-making in the face of uncertainty in anxiety.

Indexed as

AnxietyFearAnimalsAnxiety DisordersHumansReinforcement, PsychologyUncertaintyAnxietyApproach-avoidance conflictComputational modellingDecision-makingFearGenerative modelsReinforcement learningUncertainty

Identifiers

PMID36375584
PMCPMC10564627
OpenAlexW4308922277

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.