Evidence map›Paper›PMID 36376415›Full record

ArticleScientific reports2022

Inducer-free cellulase production system based on the constitutive expression of mutated XYR1 and ACE3 in the industrial fungus Trichoderma reesei.

Toshiharu Arai, Sakurako Ichinose, Nozomu Shibata, Hiroshi Kakeshita, Hiroshi Kodama, Kazuaki Igarashi, Yasushi Takimura

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. The Zn(II)2Cys6 transcription factorApplied and environmental microbiology · 2026
    Article
  3. Article
  4. Robust Production of Cellulases to Develop a Low-Cost Sugar Platform.Advances in biochemical engineering/biotechnology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Engineering cellulases for conversion of lignocellulosic biomass.Protein engineering, design & selection : PEDS · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Toshiharu AraiBiological Science Research, Kao Corporation, 1334 Minato, Wakayama, Wakayama, 640‑8580, Japan.
Sakurako IchinoseBiological Science Research, Kao Corporation, 1334 Minato, Wakayama, Wakayama, 640‑8580, Japan.
Nozomu ShibataBiological Science Research, Kao Corporation, 1334 Minato, Wakayama, Wakayama, 640‑8580, Japan.
Hiroshi KakeshitaBiological Science Research, Kao Corporation, 1334 Minato, Wakayama, Wakayama, 640‑8580, Japan. kakeshita.hiroshi@kao.com.
Hiroshi KodamaBiological Science Research, Kao Corporation, 1334 Minato, Wakayama, Wakayama, 640‑8580, Japan.
Kazuaki IgarashiBiological Science Research, Kao Corporation, 1334 Minato, Wakayama, Wakayama, 640‑8580, Japan.
Yasushi TakimuraBiological Science Research, Kao Corporation, 1334 Minato, Wakayama, Wakayama, 640‑8580, Japan.
Kao Corporation (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trichoderma reesei is a widely used host for producing cellulase and hemicellulase cocktails for lignocellulosic biomass degradation. Here, we report a genetic modification strategy for industrial T. reesei that enables enzyme production using simple glucose without inducers, such as cellulose, lactose and sophorose. Previously, the mutated XYR1

Indexed as

CellulaseTrichodermaDNAFungal ProteinsGene Expression Regulation, FungalGlucoseHypocrealesTranscription FactorsCellulaseDNAFungal ProteinsGlucoseTranscription Factors

Identifiers

PMID36376415
PMCPMC9663580
OpenAlexW4309001622

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.