Evidence map›Paper›PMID 36376558›Full record

SynthesisWorld journal of pediatrics : WJP2023

Addition of respiratory exercises to conventional rehabilitation for children and adolescents with cerebral palsy: a systematic review and meta-analysis.

Thálita Raysa de Lima Crispim, Mansueto Gomes Neto, Tafnes Rayane Lima Crispim, Renivaldo Batista Dias, Maria Déborah Monteiro de Albuquerque, Micheli Bernardone Saquetto, Paulo André Freire Magalhães

2 registry-linked trialsOpen access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in World journal of pediatrics : WJP, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07048223 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Expiratory Muscle Training on Posture, Balance, Trunk Control, and Respiratory Function in Children With Cerebral Palsy

TypeinterventionalSponsorIstinye UniversityRan2025 to 2026Enrolled20ConditionsCerebral Palsy (CP)ArmsExpiratory Muscle Training, Sham Expiratory Muscle Training
NCT07681947 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

N.E.F.E.S.-CP (Qualified Education for Awareness, Accessible Breathing: Cerebral Palsy) A Gamified Breathing and Postural Awareness Education Model

TypeinterventionalSponsorYeditepe UniversityRan2026 to 2026Enrolled40ConditionsCerebral PalsyArmsN.E.F.E.S.-CP Education Model
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Inspiratory Muscle Training in Children With Cerebral Palsy: Effects on Respiratory and Motor Functions.Pediatrics international : official journal of the Japan Pediatric Society
    Trial
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Thálita Raysa de Lima CrispimResearch Group of Neonatal and Pediatric Physical Therapy, Baby GrUPE, Petrolina, Pernambuco, Brazil. thalitaraysadelima@gmail.com.ORCID 0000-0001-5343-4919
Mansueto Gomes NetoResearch Group of Physiotherapy, Department of Physical Therapy, Universidade Federal da Bahia, Salvador, Brazil.
Tafnes Rayane Lima CrispimResearch Group of Neonatal and Pediatric Physical Therapy, Baby GrUPE, Petrolina, Pernambuco, Brazil.ORCID 0000-0003-1720-2250
Renivaldo Batista DiasResearch Group of Neonatal and Pediatric Physical Therapy, Baby GrUPE, Petrolina, Pernambuco, Brazil.ORCID 0000-0003-0151-1059
Maria Déborah Monteiro de AlbuquerqueResearch Group of Neonatal and Pediatric Physical Therapy, Baby GrUPE, Petrolina, Pernambuco, Brazil.ORCID 0000-0002-6392-2980
Micheli Bernardone SaquettoResearch Group of Physiotherapy, Department of Physical Therapy, Universidade Federal da Bahia, Salvador, Brazil.ORCID 0000-0003-3211-8102
Paulo André Freire MagalhãesResearch Group of Neonatal and Pediatric Physical Therapy, Baby GrUPE, Petrolina, Pernambuco, Brazil.ORCID 0000-0002-2224-9291
Universidade Federal da Bahia · BRInstituto Federal do Sertão Pernambucano · BRUniversidade de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory dysfunctions are an important cause of morbidity and death in cerebral palsy (CP) populations. Respiratory exercises in addition to conventional rehabilitation have been suggested to improve respiratory status in CP patients. The objective of this systematic review and meta-analysis was to verify the effects of the addition of respiratory exercises to conventional rehabilitation on pulmonary function, functional capacity, respiratory muscle strength, gross motor function and quality of life in children and adolescents with CP.

methodsWe searched for randomized controlled clinical trials in PubMed/Medline, Lilacs, SciELO, EMBASE and Physiotheraphy Evidence (PEDro) from their inception until July 2022 without language restrictions. Studies that included respiratory exercises (breathing exercise program; feedback respiratory training; incentive spirometer exercise; inspiratory muscle training; and combination of respiratory exercises + incentive spirometer exercise) in combination with conventional rehabilitation for children and adolescents with CP were evaluated by two independent reviewers. The mean difference (MD) and 95% confidence interval (CI) were estimated by random effect models.

resultsTen studies met the eligibility criteria, including 324 children aged from 6 to 16 years. The meta-analysis showed an improvement in inspiratory muscle strength of 22.96 cmH

conclusionsEmerging data show significant enhancements in inspiratory muscle strength and pulmonary function in CP patients after respiratory training in addition to conventional rehabilitation. There is no consensus on the frequency, type or intensity of respiratory exercises for children with and adolescents with CP.

Indexed as

Cerebral PalsyQuality of LifeAdolescentBreathing ExercisesChildExerciseHumansPhysical Therapy ModalitiesBreathing exercisesCerebral palsyInspiratory muscle trainingPediatricsRehabilitationRespiratory exercise

Identifiers

PMID36376558
PMCPMC9663285
OpenAlexW4309114341

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.