Evidence map›Paper›PMID 36378056›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2022

Efficacy of stimulating Mingmen (GV4) and Guanyuan (CV4) on kidney deficiency in rat model: laser irradiation traditional moxibustion.

Fang Jing, Pan Wen, Wang Xiangyun, L I Fengxing, Zhao Ling, Huang Zouqin, Shen Xueyong

Open access · greenAbstract read
In one paragraph

Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fang JingAcupuncture and Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Pan WenAcupuncture and Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Wang XiangyunAcupuncture and Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
L I FengxingAcupuncture and Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhao LingAcupuncture and Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Huang ZouqinDepartment of Acupuncture,Shanghai Pudong New District Hospital of Traditional Chinese Medicine, Shanghai 201203, China.
Shen XueyongAcupuncture and Tuina School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Shanghai University of Traditional Chinese Medicine · CNShanghai Traditional Chinese Medicine Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of 10.6-μm laser moxibustion (LM) and traditional moxibustion (TM) on kidney deficiency (KYD) model rats.

methodsForty rats were randomly divided into normal, model, 10.6-μm LM, and TM groups. KYD was induced through intramuscular hydrocortisone injections.

resultsHydrocortisone injections decreased the body weight, activity, and temperature and induced changes in the organ coefficients. Compared with the model group, TM and LM treatment prevented body weight loss and improved organ coefficients after treatment ( < 0.05), while the body weight remained lower compared to the normal group ( < 0.01). Additionally, LM and TM significantly increased the levels of urine 17-hydroxycorticosteroid (17-OHCS) compared with the model group ( < 0.01). The LM and TM groups showed a greater distance travelled across the central area, time spent in the central area, and 5-min total distance than the model group in the open field test ( < 0.01). The model group had the lowest anal or surface temperature ( < 0.05); there were no differences among the other three groups ( > 0.05). TM treatment increased the temperature of Mingmen (GV4) and Guanyuan (CV4) compared to the model group ( < 0.05, < 0.01). LM treatment increased Mingmen (GV4) temperature ( < 0.05), while there were no obvious differences in Guanyuan (CV4) temperature compared with the normal group before and after treatment ( > 0.05). There was a positive correlation between Mingmen (GV4)/Guanyuan (CV4) temperature and 17-OHCS levels.

conclusionsLM and TM treatment can improve KYD symptoms, and acupoint temperature changes may be an objective indicator of KYD.

Indexed as

MoxibustionAcupuncture PointsAnimalsBody WeightHydrocortisoneKidneyRatsHydrocortisoneacupointshydrocortisoneKidney- deficiencylaser moxibustionmicro-circulationtemperature

Identifiers

PMID36378056
PMCPMC9924713
OpenAlexW4309361797

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.