Evidence map›Paper›PMID 36378446›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Identification of Subproteomic Markers for Skeletal Muscle Profiling.

Paul Dowling, Stephen Gargan, Dieter Swandulla, Kay Ohlendieck

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Serum protein biomarker signature of Duchenne muscular dystrophy.European journal of translational myology · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paul DowlingDepartment of Biology, Maynooth University, National University of Ireland, Maynooth, Co. Kildare, Ireland.
Stephen GarganDepartment of Biology, Maynooth University, National University of Ireland, Maynooth, Co. Kildare, Ireland.
Dieter SwandullaInstitute of Physiology, University of Bonn, Bonn, Germany.
Kay OhlendieckDepartment of Biology, Maynooth University, National University of Ireland, Maynooth, Co. Kildare, Ireland. kay.ohlendieck@mu.ie.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biochemical and cell biological profiling of contractile fiber types and subcellular structures plays a central role in basic and applied myology. Mass spectrometry-based proteomics presents an ideal approach for the systematic identification of proteomic and subproteomic markers. These representative components of fast versus slow muscle fibers and their subcellular fractions are highly useful for in-depth surveys of skeletal muscle adaptations to physiological challenges, as well as the improvement of diagnostic, prognostic, and therapy-monitoring methodologies in muscle pathology. This chapter outlines the identification of subproteomic markers for skeletal muscle profiling based on bottom-up and top-down approaches, including fluorescence two-dimensional difference gel electrophoresis (2D-DIGE).

Indexed as

Muscle ProteinsProteomicsBiomarkersElectrophoresis, Gel, Two-DimensionalMass SpectrometryMuscle, SkeletalProteomeTwo-Dimensional Difference Gel ElectrophoresisBiomarkersMuscle ProteinsProteomeDIGEProteomicsSkeletal muscleSubcellular markerSubproteomics

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.