ReviewCell genomics2022
Uganda Genome Resource: A rich research database for genomic studies of communicable and non-communicable diseases in Africa.
Review in Cell genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- KidneyGenAfrica multi-cohort Genome-wide association study and polygenic prediction of kidney function in 110,000 Africans.Nature communications · 2026Pooled it
- Accounting for heterogeneity due to environmental sources in meta-analysis of genome-wide association studies.Communications biology · 2024Pooled it
- Neuropsychiatry genetics in Africa.Nature communications · 2026Review
- Pleiotropy and eQTL analysis identify shared genetic architecture of lipid traits in African-ancestry populations.Human molecular genetics · 2026Article
- Genetic associations with alcohol drinking initiation and cessation in sub-Saharan African and African ancestry populations.Research square · 2026Article
- Local implementation of scalable malaria molecular surveillance in a low-resource setting: a North-South collaborative model.Malaria journal · 2026Article
- National genomic projects in Asia and Africa: a review.Human genomics · 2026Review
- Ancestral diversity in complex disease genetics: from discovery to translation.Nature reviews. Genetics · 2026Review
- Navigating the human gene editing scene and proposing a new governance framework in Africa: from knowledge to policy to action.Frontiers in genome editing · 2026Article
- Linking the plasma proteome to genetics in individuals from continental Africa provides insights into type 2 diabetes pathogenesis.Nature genetics · 2026Article
- Polygenic prediction of body mass index and obesity through the life course and across ancestries.Nature medicine · 2025Article
- The impact of ancestry on performance of type 1 diabetes genetic risk scores: high discrimination performance is maintained in African ancestry populations, but population specific thresholds may improve risk prediction.medRxiv : the preprint server for health sciences · 2025Article
- Development and Validation of Polygenic Risk Scores for Blood Pressure Traits in Continental African Populations.Circulation. Genomic and precision medicine · 2025Article
- Driving Global Health equity and precision medicine through African genomic data.Human molecular genetics · 2025Article
- GWAShug: a comprehensive platform for decoding the shared genetic basis between complex traits based on summary statistics.Nucleic acids research · 2025Article
- Prevalence and correlates of common mental disorders among participants of the Uganda Genome Resource: Opportunities for psychiatric genetics research.Molecular psychiatry · 2025Article
- Phenome-wide association study and functional annotation of hemoglobin A1c-associated variants in African populations.PloS one · 2025Article
- Big data in sarcoidosis.Current opinion in pulmonary medicine · 2024Review
- The Value Proposition of Coordinated Population Cohorts Across Africa.Annual review of biomedical data science · 2024Review
- CoPheScan: phenome-wide association studies accounting for linkage disequilibrium.Nature communications · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
The Uganda Genome Resource (UGR) is a well-characterized genomic database with a range of phenotypic communicable and non-communicable diseases and risk factors generated from the Uganda General Population Cohort (GPC), a population-based open cohort established in 1989. The UGR comprises genotype data on ∼5,000 and whole-genome sequence data on ∼2,000 Ugandan GPC individuals from 10 ethno-linguistic groups. Leveraging other platforms at MRC/UVRI and LSHTM Uganda Research Unit, there is opportunity for additional sample collection to expand the UGR to advance scientific discoveries. Here, we describe UGR and highlight how it is providing opportunities for discovery of novel disease susceptibility genetic loci, refining association signals at new and existing loci, developing and testing polygenic scores to determine disease risk, assessing causal relations in diseases, and developing capacity for genomics research in Africa. The UGR has the potential to develop to a comparable level of European and Asian large-scale genomic initiatives.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.