Evidence map›Paper›PMID 36401124›Full record

ArticlePediatric cardiology2024

Vascular Health in Adults Born After Using Assisted Reproductive Technologies.

Magdalena Langer, Theresa Vilsmaier, Marie Kramer, Franziska Sciuk, Brenda Kolbinger, Pengzhu Li, André Jakob, Nina Rogenhofer, Robert Dalla-Pozza, Christian Thaler and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Pediatric cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Vascular Health of Females with History of Assisted Reproductive Technology.Journal of cardiovascular development and disease · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Magdalena LangerDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
Theresa VilsmaierDivision of Gynecological Endocrinology and Reproductive Medicine, Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Marie KramerDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
Franziska SciukDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
Brenda KolbingerDivision of Gynecological Endocrinology and Reproductive Medicine, Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Pengzhu LiDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
André JakobDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
Nina RogenhoferDivision of Gynecological Endocrinology and Reproductive Medicine, Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Robert Dalla-PozzaDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
Christian ThalerDivision of Gynecological Endocrinology and Reproductive Medicine, Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Nikolaus Alexander HaasDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
Felix Sebastian OberhofferDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany. Felix.Oberhoffer@med.uni-muenchen.de.
LMU Klinikum · DELudwig-Maximilians-Universität München · DE

Funding

Deutsche Forschungsgemeinschaft 413635475
6 · The paper itself

Abstract

An increasing number of children are conceived by assisted reproductive technologies (ART). Several studies indicated vascular alterations in ART children. However, limited data is available within the adult ART population. Therefore, this study investigated the overall vascular health of young ART adults in comparison to spontaneously conceived peers. In total, 16 ART subjects and 22 spontaneously conceived peers (22.06 ± 2.21 years vs. 22.00 ± 2.14 years, p = 0.194) were enrolled for the assessment of endothelial function, brachial blood pressure, central blood pressure, pulse wave velocity, carotid intima-media thickness, and blood lipids. No significant differences in vascular function were detected between the in vitro fertilization subgroup (n = 9), the intracytoplasmic sperm injection subgroup (n = 7) and spontaneously conceived peers. This pilot study suggests an unimpaired vascular function in young ART adults. In the future, multi-centric studies with a greater sample size are required to confirm the results of the current study and enable precise cardiovascular risk stratification of the adult ART population.

Indexed as

Carotid Intima-Media ThicknessPulse Wave AnalysisReproductive Techniques, AssistedAdultBlood PressureCardiovascular DiseasesEndothelium, VascularFemaleFertilization in VitroHumansLipidsMalePilot ProjectsSperm Injections, IntracytoplasmicYoung AdultLipidsArterial stiffnessAssisted reproductive technologiesBlood pressureEndothelial functionVascular health

Identifiers

PMID36401124
PMCPMC11252174
OpenAlexW4309359261

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.