Evidence map›Paper›PMID 36405717›Full record

ArticleFrontiers in immunology2022

H11-induced immunoprotection is predominantly linked to N-glycan moieties during

Chunqun Wang, Lu Liu, Tianjiao Wang, Xin Liu, Wenjie Peng, Ratnesh Kumar Srivastav, Xing-Quan Zhu, Nishith Gupta, Robin B Gasser, Min Hu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  6. Dual roles ofFrontiers in immunology · 2025
    Article
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  9. Review
  10. Article
  11. Article
  12. Article
  13. Genome-Wide Analysis ofInternational journal of molecular sciences · 2023
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Chunqun WangState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Lu LiuState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Tianjiao WangState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Xin LiuCollege of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Wenjie PengShanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.
Ratnesh Kumar SrivastavDepartment of Biological Sciences, Birla Institute of Technology and Science - Pilani (BITS-P), Hyderabad, India.
Xing-Quan ZhuCollege of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, China.
Nishith GuptaState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Robin B GasserMelbourne Veterinary School, The University of Melbourne, Parkville, VIC, Australia.
Min HuState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
Huazhong Agricultural University · CNBirla Institute of Technology and Science, Pilani · INHuazhong University of Science and Technology · CNHumboldt-Universität zu Berlin · DEShanghai Jiao Tong University · CNShanxi Agricultural University · CNUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nematodes are one of the largest groups of animals on the planet. Many of them are major pathogens of humans, animals and plants, and cause destructive diseases and socioeconomic losses worldwide. Despite their adverse impacts on human health and agriculture, nematodes can be challenging to control, because anthelmintic treatments do not prevent re-infection, and excessive treatment has led to widespread drug resistance in nematode populations. Indeed, many nematode species of livestock animals have become resistant to almost all classes of anthelmintics used. Most efforts to develop commercial anti-nematode vaccines (native or recombinant) for use in animals and humans have not succeeded, although one effective (dead) vaccine (Barbervax) has been developed to protect animals against one of the most pathogenic parasites of livestock animals -

Indexed as

AnthelminticsHaemonchiasisHaemonchusVaccinesAnimalsHumansImmunoglobulin GPolysaccharidesAnthelminticsImmunoglobulin GPolysaccharidesVaccinesH11 antigenIgG antibodiesimmunoprotectionN-glycanN-glycosylationparasitic nematodevaccine

Identifiers

PMID36405717
PMCPMC9667387
OpenAlexW4307372252

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.