Evidence map›Paper›PMID 36409061›Full record

ArticleBrain and behavior2022

Clinical outcomes and cognitive impairments between progressive supranuclear palsy and multiple system atrophy.

Peifei Jia, Jinhong Zhang, Jiuyan Han, Yong Ji

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Pathomechanisms of cognitive impairment in progressive supranuclear palsy.Journal of neural transmission (Vienna, Austria : 1996) · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Peifei JiaClinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.
Jinhong ZhangClinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, China.ORCID 0000-0003-4741-3040
Jiuyan HanDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yong JiDepartment of Neurology, Tianjin Huanhu Hospital, Tianjin, China.
Capital Medical University · CNBaotou Medical College · CNPeople's Hospital of Cangzhou · CN

Funding

National Natural Science Foundation 821722820Science and Technology Project of Tianjin Municipal Health and Health Committee KJ20048Science and Technology Project of Tianjin Municipal Health and Health Committee ZC20121
6 · The paper itself

Abstract

backgroundBoth progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) belong to atypical parkinsonian syndromes. It is important to differentiate these diseases accurately. We compared clinical outcomes and cognitive impairments between PSP and MSA.

methodsEighty-five MSA parkinsonism type (MSA-P) patients and 76 PSP patients participated in this research. The Montreal Cognitive Assessment (MoCA) and the mini-mental state examination (MMSE) evaluated cognitive function.

resultsMSA-P patients had a significantly higher incidence of dyskinesia, fall, urinary symptoms, and constipation, whereas patients with PSP had a higher incidence of tremor and salivation. MSA-P patients had higher MMSE and MoCA scores than PSP patients. The MMSE score showed a diagnostic cut-off score of 24.5 in PSP versus MSA-P. The MoCA score showed a diagnostic cut-off score of 20.5 in PSP versus MSA-P.

conclusionIn conclusion, patients with PSP had differences in the clinical outcomes and cognitive impairments compared with MSA-P patients. PSP patients had more severe cognitive deficits. The score of MMSE and MoCA could be used in distinguishing MSA-P from PSP.

Indexed as

Cognitive DysfunctionMultiple System AtrophyParkinsonian DisordersSupranuclear Palsy, ProgressiveHumansMental Status and Dementia Testscognitive impairmentsmultiple system atrophyprogressive supranuclear palsythe mini-mental state examinationthe Montreal Cognitive Assessment

Identifiers

PMID36409061
PMCPMC9759125
OpenAlexW4309509749

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.