Evidence mapPaperPMID 36419795Full record

SynthesisFrontiers in medicine2022

Venous thromboembolism in in-hospital cirrhotic patients: A systematic review.

Leonardo da Cruz Renó, Francisco Tustumi, Daniel Reis Waisberg, Vinicius Rocha-Santos, Rafael Soares Pinheiro, Rubens Arantes Macedo, Lucas Souto Nacif, Liliana Ducatti, Rodrigo Bronze De Martino, Alexandre Maximiliano Trevisan and 2 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Leonardo da Cruz RenóTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Francisco TustumiTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Daniel Reis WaisbergTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Vinicius Rocha-SantosTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Rafael Soares PinheiroTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Rubens Arantes MacedoTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Lucas Souto NacifTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Liliana DucattiTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Rodrigo Bronze De MartinoTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Alexandre Maximiliano TrevisanTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Luiz Carneiro-D'AlbuquerqueTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Wellington AndrausTransplantation Unit, Department of Gastroenterology, Universidade de São Paulo, São Paulo, Brazil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Patients with liver cirrhosis are at a higher risk of hospitalization. The present review aimed to assess the risk of thromboembolism and its burden on hospitalized cirrhotic patients. Materials and methods: A systematic review (PROSPERO: CRD42021256869) was conducted in PubMed, Embase, Cochrane, Lilacs, and a manual search of references. It evaluated studies that compare cirrhotic patients with venous thromboembolism (VTE) with cirrhotic patients without VTE or studies that compare cirrhotic patients with non-cirrhotic patients. No restrictions were set for the date of publication or language. The last search was conducted in June 2021. Results: After selection, 17 studies were included from an initial search of 5,323 articles. The chronic liver disease etiologies comprise viral, alcohol, autoimmune, NASH (non-alcoholic steatohepatitis), cryptogenic, hemochromatosis, cholestasis, and drug-related. The included studies were conflicted regarding the outcomes of VTE, pulmonary embolism, or bleeding. Patients with cirrhosis associated with VTE had prolonged length of hospital stay, and patients with cirrhosis were at higher risk of portal thrombosis. Conclusion: In-hospital cirrhotic patients are a heterogeneous group of patients that may present both thrombosis and bleeding risk. Clinicians should take extra caution to apply both prophylactic and therapeutic anticoagulation strategies. Systematic review registration: [https://www.crd.york.ac.uk/PROSPERO/], identifier [CRD42021256869].

Indexed as

bleedingliverliver cirrhosissystematic reviewvenous thrombosis

Identifiers

PMID36419795
PMCPMC9676642
OpenAlexW4308451481

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.