Evidence map›Paper›PMID 36419932›Full record

ArticleFrontiers in molecular biosciences2022

Molecular determinants of the interaction between HSV-1 glycoprotein D and heparan sulfate.

Lauren A Gandy, Ashley J Canning, Huan Lou, Ke Xia, Peng He, Guowei Su, Tina Cairns, Jian Liu, Fuming Zhang, Robert J Linhardt and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lauren A GandyCenter for Biotechnology and Interdisciplinary Studies, Troy, NY, United States.
Ashley J CanningCenter for Biotechnology and Interdisciplinary Studies, Troy, NY, United States.
Huan LouDepartment of Microbiology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Ke XiaCenter for Biotechnology and Interdisciplinary Studies, Troy, NY, United States.
Peng HeCenter for Biotechnology and Interdisciplinary Studies, Troy, NY, United States.
Guowei SuGlycan Therapeutics, Raleigh, NC, United States.
Tina CairnsDepartment of Microbiology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Jian LiuGlycan Therapeutics, Raleigh, NC, United States.
Fuming ZhangCenter for Biotechnology and Interdisciplinary Studies, Troy, NY, United States.
Robert J LinhardtCenter for Biotechnology and Interdisciplinary Studies, Troy, NY, United States.
Gary CohenDepartment of Microbiology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Chunyu WangCenter for Biotechnology and Interdisciplinary Studies, Troy, NY, United States.
Rensselaer Polytechnic Institute · USUniversity of Pennsylvania · USUniversity of North Carolina at Chapel Hill · US

Funding

Heparan Sulfate 3-O-Sulfation in Transcellular Propagation of Tauopathy in Alzheimer's DiseaseRF1AG069039 · NIA · RENSSELAER POLYTECHNIC INSTITUTE · PI LINHARDT, ROBERT J, LIU, JIAN · 2020 to 2020
$2.6M
The Alzheimer's Disease Clinical and Translational Research (ADCTR) Training ProgramT32AG057464 · NIA · RENSSELAER POLYTECHNIC INSTITUTE · PI WANG, CHUNYU · 2017 to 2021
$1.6M
Predoctoral Training Program for Alzheimer’s Disease at the Interface of Data Science, Engineering and BiologyT32AG078123 · NIA · RENSSELAER POLYTECHNIC INSTITUTE · PI Chunyu Wang · 2023 to 2026
$974k
Biacore T200 Surface Plasmon Resonance SpectroscopyS10OD028523 · OD · RENSSELAER POLYTECHNIC INSTITUTE · PI LINHARDT, ROBERT J · 2020 to 2020
$344k
NIA NIH HHS RF1 AG069039NIA NIH HHS T32 AG057464NIA NIH HHS T32 AG078123NIH HHS S10 OD028523
6 · The paper itself

Abstract

Literature has well-established the importance of 3-

Indexed as

glycoprotein Dheparan sulfateheparinherpesHSV-1

Identifiers

PMID36419932
PMCPMC9678342
OpenAlexW4308448252

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.