Evidence map›Paper›PMID 36422255›Full record

ArticleMetabolites2022

Does the Hyperglycemia Impact on COVID-19 Outcomes Depend upon the Presence of Diabetes?-An Observational Study.

Inês Manique, Alexandra Abegão Matias, Bruno Bouça, Teresa Rego, Luísa Cortez, Teresa Sabino, António Panarra, Manfredi Rizzo, José Silva-Nunes

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Insulin Resistance in Long COVID-19 Syndrome.Journal of personalized medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Inês ManiqueDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário Lisboa Central, Hospital de Curry Cabral, 1050-099 Lisbon, Portugal.
Alexandra Abegão MatiasDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário Lisboa Central, Hospital de Curry Cabral, 1050-099 Lisbon, Portugal.
Bruno BouçaDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário Lisboa Central, Hospital de Curry Cabral, 1050-099 Lisbon, Portugal.ORCID 0000-0002-1192-7915
Teresa RegoDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário Lisboa Central, Hospital de Curry Cabral, 1050-099 Lisbon, Portugal.
Luísa CortezDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário Lisboa Central, Hospital de Curry Cabral, 1050-099 Lisbon, Portugal.
Teresa SabinoDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário Lisboa Central, Hospital de Curry Cabral, 1050-099 Lisbon, Portugal.
António PanarraFunctional Unit of Internal Medicine 7.2, Centro Hospitalar Universitário Lisboa Central, Hospital de Curry Cabral, 1050-099 Lisbon, Portugal.
Manfredi RizzoDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, School of Medicine, University of Palermo, 90100 Palermo, Italy.ORCID 0000-0002-9549-8504
José Silva-NunesDepartment of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário Lisboa Central, Hospital de Curry Cabral, 1050-099 Lisbon, Portugal.
Hospital Curry Cabral · PTInstituto Politécnico de Lisboa · PTUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM) has emerged as a major risk factor for COVID-19 severity and SARS-CoV-2 infection can worsen glycemic control and may precipitate new-onset diabetes. At-admission hyperglycemia (AH) is a known predictor for worse outcomes in many diseases and seems to have a similar effect in COVID-19 patients. In this study, we aimed to assess the impact of AH regardless of pre-existing diabetes mellitus and new-onset diabetes diagnosis in the clinical severity of COVID-19 inpatients in the first months of the pandemic. A retrospective monocentric study on 374 COVID-19 inpatients (209 males) was developed to assess associations between AH (blood glucose levels in the Emergency Department or the first 24 h of hospitalization greater than 140 mg/dL) and severity outcomes (disease severity, respiratory support, admission to Intensive Care Unit (ICU) and mortality) in patients with and without diabetes. Considering diabetic patients with AH (N = 68;18.1%) there was a correlation with COVID-19 severity (

Indexed as

clinical outcomesCOVID-19diabetes mellitushyperglycemia

Identifiers

PMID36422255
PMCPMC9693757
OpenAlexW4309312270

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.