Evidence map›Paper›PMID 36424581›Full record

ArticleBMC pulmonary medicine2022

Two-dimensional shear wave elastography: a new tool for evaluating respiratory muscle stiffness in chronic obstructive pulmonary disease patients.

Yongjian Chen, Jingyun Li, Bingtian Dong, Zhixing Zhu, Guorong Lyu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07024095 ("Effects of Inspiratory Muscle Training on Pulmonary Function, Functional Capacity, and Quality of Life After Percutaneous Vertebroplasty in Individuals With Osteoporotic Vertebral Compression Fracture"), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07024095 narecruitingnot on this mapstarted 2025, after this paper: background citation

"Effects of Inspiratory Muscle Training on Pulmonary Function, Functional Capacity, and Quality of Life After Percutaneous Vertebroplasty in Individuals With Osteoporotic Vertebral Compression Fracture"

TypeinterventionalSponsorIstinye UniversityRan2025 to 2026Enrolled24ConditionsOsteoporotic Vertebral Compression Fractures, Restrictive Pulmonary Disorders, Inspiratory Muscle Weakness, Postoperative Pulmonary FunctionArmsInspiratory Muscle Training (IMT), control group
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Considerations of emerging diaphragmatic ultrasound techniques for clinical practice: potential pitfalls and future challenges.European respiratory review : an official journal of the European Respiratory Society · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Ultrasound innovations in diaphragm assessment: an integrative review of expanding clinical applications.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yongjian ChenDepartment of Ultrasound, the Second Affiliated Hospital of Fujian Medical University, No. 34 North Zhongshan Road, Licheng District, 362000, Quanzhou, Fujian, China.
Jingyun LiQuanzhou Medical College, No. 2 Anji Road, Luojiang District, 362000, Quanzhou, Fujian Province, China.
Bingtian DongDepartment of Ultrasound, the Second Affiliated Hospital of Fujian Medical University, No. 34 North Zhongshan Road, Licheng District, 362000, Quanzhou, Fujian, China.
Zhixing ZhuDepartment of Pulmonary and Critical Care Medicine, the Second Affiliated Hospital of Fujian Medical University, No. 34 North Zhongshan Road, Licheng District, 362000, Quanzhou, Fujian, China.
Guorong LyuDepartment of Ultrasound, the Second Affiliated Hospital of Fujian Medical University, No. 34 North Zhongshan Road, Licheng District, 362000, Quanzhou, Fujian, China. lgr_feus@sina.com.
Quanzhou Normal University · CNSecond Affiliated Hospital of Fujian Medical University · CNFujian Medical University · CN

Funding

Natural Science Foundation of Fujian Province,China NO:2022J01783
6 · The paper itself

Abstract

backgroundImpaired respiratory function caused by respiratory muscle dysfunction is one of the common consequences of chronic obstructive pulmonary disease (COPD). In this study, two-dimensional shear wave elastography (2D-SWE) was used to measure diaphragm stiffness (DS) and intercostal muscle stiffness (IMS) in patients with COPD; in addition, the value of 2D-SWE in evaluating respiratory function was determined.

methodsIn total, 219 consecutive patients with COPD and 20 healthy adults were included. 2D-SWE was used to measure the DS and IMS, and lung function was also measured. The correlation between respiratory muscle stiffness and lung function and the differences in respiratory muscle stiffness in COPD patients with different severities were analysed.

results2D-SWE measurements of the DS and IMS presented with high repeatability and consistency, with ICCs of 0.756 and 0.876, respectively, and average differences between physicians of 0.10 ± 1.61 and 0.07 ± 1.65, respectively. In patients with COPD, the DS and IMS increased with disease severity (F

conclusion2D-SWE has potential for use in evaluating DS and IMS. A specific correlation was observed between respiratory muscle stiffness and lung function. With the worsening of the severity of COPD and the progression of lung function impairment, the DS and IMS gradually increased.

Indexed as

Elasticity Imaging TechniquesPulmonary Disease, Chronic ObstructiveAdultHumansRespiratory Function TestsRespiratory MusclesRespiratory SystemChronic obstructive pulmonary diseaseDiaphragm stiffnessIntercostal muscle stiffnessLung functionTwo-dimensional shear wave elastography

Identifiers

PMID36424581
PMCPMC9686016
OpenAlexW4309889634

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.