Evidence map›Paper›PMID 36430982›Full record

ArticleLife (Basel, Switzerland)2022

The Combination of Whole-Brain Features and Local-Lesion Features in DSC-PWI May Improve Ischemic Stroke Outcome Prediction.

Yingwei Guo, Yingjian Yang, Mingming Wang, Yu Luo, Jia Guo, Fengqiu Cao, Jiaxi Lu, Xueqiang Zeng, Xiaoqiang Miao, Asim Zaman and 1 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yingwei GuoCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.ORCID 0000-0002-3049-8474
Yingjian YangCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.ORCID 0000-0002-7425-1297
Mingming WangDepartment of Radiology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai 200434, China.
Yu LuoDepartment of Radiology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai 200434, China.
Jia GuoDepartment of Psychiatry, Columbia University, New York, NY 10027, USA.ORCID 0000-0003-4803-0279
Fengqiu CaoCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.
Jiaxi LuCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen 518118, China.
Xueqiang ZengCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen 518118, China.
Xiaoqiang MiaoCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.
Asim ZamanCollege of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen 518118, China.ORCID 0000-0002-7723-3684
Yan KangCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China.ORCID 0000-0002-4532-5744

Funding

National Natural Science Foundation of China 62071311Scientific Research Fund of Liaoning Province of China JL201919Stable Support Plan for Colleges and Universities in Shenzhen of China SZWD2021010the special program for key fields of colleges and universities in Guangdong Province (biomed-icine and health) of China 2021ZDZX2008
6 · The paper itself

Abstract

Accurate and reliable outcome predictions can help evaluate the functional recovery of ischemic stroke patients and assist in making treatment plans. Given that recovery factors may be hidden in the whole-brain features, this study aims to validate the role of dynamic radiomics features (DRFs) in the whole brain, DRFs in local ischemic lesions, and their combination in predicting functional outcomes of ischemic stroke patients. First, the DRFs in the whole brain and the DRFs in local lesions of dynamic susceptibility contrast-enhanced perfusion-weighted imaging (DSC-PWI) images are calculated. Second, the least absolute shrinkage and selection operator (Lasso) is used to generate four groups of DRFs, including the outstanding DRFs in the whole brain (Lasso (WB)), the outstanding DRFs in local lesions (Lasso (LL)), the combination of them (combined DRFs), and the outstanding DRFs in the combined DRFs (Lasso (combined)). Then, the performance of the four groups of DRFs is evaluated to predict the functional recovery in three months. As a result, Lasso (combined) in the four groups achieves the best AUC score of 0.971, which improves the score by 8.9% compared with Lasso (WB), and by 3.5% compared with Lasso (WB) and combined DRFs. In conclusion, the outstanding combined DRFs generated from the outstanding DRFs in the whole brain and local lesions can predict functional outcomes in ischemic stroke patients better than the single DRFs in the whole brain or local lesions.

Indexed as

DSC-PWIdynamic radiomics featureslassolocal lesionsoutcome predictionwhole brain

Identifiers

PMID36430982
PMCPMC9694195

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.