Evidence map›Paper›PMID 36439147›Full record

ArticleFrontiers in immunology2022

Characterizing and correcting immune dysfunction in non-tuberculous mycobacterial disease.

Champa N Ratnatunga, Katie Tungatt, Carla Proietti, Sam Halstrom, Michael R Holt, Viviana P Lutzky, Patricia Price, Denise L Doolan, Scott C Bell, Matt A Field and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
  4. CD226 identifies effector CD8Cell reports · 2025
    Article
  5. Cell Death Mechanisms inPathogens (Basel, Switzerland) · 2025
    Review
  6. Article
  7. One health (Amsterdam, Netherlands) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 3 countries.

Champa N RatnatungaAustralian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia.
Katie TungattAustralian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia.
Carla ProiettiAustralian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia.
Sam HalstromCurtin Medical School, Curtin University, Perth, WA, Australia.
Michael R HoltSchool of Medicine, University of Queensland, Brisbane, QLD, Australia.
Viviana P LutzkyQueensland Institute of Medical Research (QIMR) Berghofer, Brisbane, QLD, Australia.
Patricia PriceCurtin Medical School, Curtin University, Perth, WA, Australia.
Denise L DoolanAustralian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia.
Scott C BellSchool of Medicine, University of Queensland, Brisbane, QLD, Australia.
Matt A FieldAustralian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia.
Andreas KupzAustralian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia.
Rachel M ThomsonSchool of Medicine, University of Queensland, Brisbane, QLD, Australia.
John J MilesAustralian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia.
James Cook University · AUAustralian Institute of Tropical Health and Medicine · AUCurtin University · AUQIMR Berghofer Medical Research Institute · AUCardiff University · GBGreenslopes Private Hospital · AUPrince Charles Hospital · AUUniversity Hospital of Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-tuberculous mycobacterial pulmonary disease (NTM-PD) is a chronic, progressive, and growing worldwide health burden associated with mounting morbidity, mortality, and economic costs. Improvements in NTM-PD management are urgently needed, which requires a better understanding of fundamental immunopathology. Here, we examine temporal dynamics of the immune compartment during NTM-PD caused by

Indexed as

Immune System DiseasesLung DiseasesMycobacterium avium-intracellulare InfectionHumansMycobacterium avium ComplexNontuberculous Mycobacteriahigh-dimensional immunoprofilingimmune cell dysfunctionimmune modulationmycobacterial immunitynon-tuberculous mycobacteria

Identifiers

PMID36439147
PMCPMC9686449
OpenAlexW4308873032

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.