ArticleFrontiers in endocrinology2022
Life-course blood pressure trajectories and incident diabetes: A longitudinal cohort in a Chinese population.
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 7 citations in OpenAlex.
- Trajectories of blood pressure and influencing factors across menopause: A longitudinal cohort study.American journal of preventive cardiology · 2026Article
- Impact of growth markers and patterns of growth on children's cardiometabolic health: a life course perspective.World journal of pediatrics : WJP · 2026Article
- The role of hypertension in mediating the relationship between overweight and obesity and diabetes: a longitudinal study.BMC public health · 2025Article
- Article
- Consistency between the geographic distributions of overweight and obesity among children and adults in China.BMC public health · 2025Article
- Blood Pressure Levels During Pregnancy and Gestational Diabetes Mellitus: A Prospective Cohort Study and Mendelian Randomization Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Transition between cardiometabolic conditions and body weight among women: which paths increase the risk of diabetes and cardiovascular diseases?Journal of human hypertension · 2024Article
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8 authors at 2 institutions in 1 country.
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Abstract
Background: Blood pressure levels are correlated with diabetes among middle-aged or older adults. However, longitudinal trajectories of blood pressure during young adulthood and their impact on diabetes have been insufficiently studied. Methods: The longitudinal cohort consisted of 4,625 adults who had blood pressure and body mass index (BMI) repeatedly measured five to nine times during 18-60 years of age. Distinct systolic blood pressure (SBP) trajectories were identified by a group-based trajectory model. Logistic regression analyses were used to investigate the association between trajectory patterns or quartiles of area under the curve values of SBP trajectories and incident diabetes, respectively. Results: Four distinct trajectory groups were identified for SBP: normotensive-stable (n = 761, 16.5%), prehypertension-stable (n = 2,381, 51.5%), stage I hypertension-increasing (n = 1,231, 26.6%), and stage II hypertension-increasing (n = 251, 5.4%). Compared with subjects who remained at SBP <120 mmHg in the normotensive-stable group, individuals in the prehypertension-stable trajectory exhibited a normal SBP range (<140 mmHg), and they still had a significantly higher risk of diabetes (adjusted OR = 1.82, p = 0.029). Individuals had a greater risk of diabetes in the stage I hypertension-increasing group (adjusted OR = 2.31, p = 0.006) and the highest risk in the stage II hypertension-increasing group (adjusted OR = 3.91, p < 0.001) relative to the normotensive-stable group. Furthermore, compared with the first quartile, adjusted ORs (95% CIs) of the fourth quartile of SBP incremental and total AUC were 2.50 (1.61-3.97) and 1.82 (1.15-2.94), respectively. Conclusions: Long-term SBP trajectory is a significant predictor for incident diabetes, which is independent of baseline SBP and body weight, attaching importance to maintaining optimal blood pressure levels and controlling changing slopes of SBP for preventing diabetes.
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