Evidence map›Paper›PMID 36442615›Full record

ArticleJournal of controlled release : official journal of the Controlled Release Society2023

Hepatic targeting of the centrally active cannabinoid 1 receptor (CB

Shira Hirsch, Liad Hinden, Meital Ben-David Naim, Saja Baraghithy, Anna Permyakova, Shahar Azar, Taher Nasser, Emma Portnoy, Majd Agbaria, Alina Nemirovski and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of controlled release : official journal of the Controlled Release Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Nanomaterials (Basel, Switzerland) · 2025
    Review
  5. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Shira HirschObesity and Metabolism Laboratory, POB 12065, Jerusalem 9112001, Israel.
Liad HindenObesity and Metabolism Laboratory, POB 12065, Jerusalem 9112001, Israel.
Meital Ben-David NaimThe Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel.
Saja BaraghithyObesity and Metabolism Laboratory, POB 12065, Jerusalem 9112001, Israel.
Anna PermyakovaObesity and Metabolism Laboratory, POB 12065, Jerusalem 9112001, Israel.
Shahar AzarObesity and Metabolism Laboratory, POB 12065, Jerusalem 9112001, Israel.
Taher NasserThe Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel.
Emma PortnoyDepartment of Biochemistry, Institute for Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Israel.
Majd AgbariaThe Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel.
Alina NemirovskiThe Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel.
Gershon GolombThe Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel.
Joseph TamObesity and Metabolism Laboratory, POB 12065, Jerusalem 9112001, Israel; The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel. Electronic address: yossi.tam@mail.huji.ac.il.
Hebrew University of Jerusalem · IL

Funding

European Research Council 101100628
6 · The paper itself

Abstract

Over-activation of the endocannabinoid/CB

Indexed as

CannabinoidsDiabetes Mellitus, Type 2Non-alcoholic Fatty Liver DiseaseAnimalsCannabinoid Receptor AntagonistsMiceObesityRimonabantCannabinoid Receptor AntagonistsCannabinoidsRimonabantCB1 receptor blockerDrug delivery systemHepatic steatosisInsulin resistanceNanomedicineObesityPolymeric nanoparticles

Identifiers

PMID36442615
PMCPMC9900386
OpenAlexW4312084119

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.