Evidence map›Paper›PMID 36444862›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2023

Spiro heterocycles bearing piperidine moiety as potential scaffold for antileishmanial activity: synthesis, biological evaluation, and

Mounir A A Mohamed, Asmaa M Kadry, Salma A Bekhit, Mohammed A S Abourehab, Kikuko Amagase, Tamer M Ibrahim, Ahmed M M El-Saghier, Adnan A Bekhit

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 38 citations in OpenAlex.

  1. NovelPharmaceuticals (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Mounir A A MohamedChemistry Department, Faculty of Science, Sohag University, Sohag, Egypt.
Asmaa M KadryChemistry Department, Faculty of Science, Sohag University, Sohag, Egypt.
Salma A BekhitHigh Institute of Public Health, Alexandria University, Alexandria, Egypt.
Mohammed A S AbourehabDepartment of Pharmaceutics, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Kikuko AmagaseLaboratory of Pharmacology & Pharmacotherapeutics, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Japan.
Tamer M IbrahimDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafr El-Sheikh, Egypt.
Ahmed M M El-SaghierChemistry Department, Faculty of Science, Sohag University, Sohag, Egypt.
Adnan A BekhitDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Sohag University · EGAlexandria University · EGApplied Nanotech (United States) · USKafrelsheikh University · EGRitsumeikan University · JPUmm al-Qura University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New spiro-piperidine derivatives were synthesised via the eco-friendly ionic liquids in a one-pot fashion. The

Indexed as

Antiprotozoal AgentsAnimalsChlorocebus aethiopsPhosphorylcholinePiperidinesVero CellsAntiprotozoal AgentsmiltefosinePhosphorylcholinePiperidinesionic liquidleishmaniamodellingpiperidineSpiro

Identifiers

PMID36444862
PMCPMC11003478
OpenAlexW4310239730

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.