Evidence map›Paper›PMID 36446587›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Synaptic Development in Diverse Olfactory Neuron Classes Uses Distinct Temporal and Activity-Related Programs.

Michael A Aimino, Alison T DePew, Lucas Restrepo, Timothy J Mosca

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael A AiminoDepartment of Neuroscience, Vickie and Jack Farber Institute of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Alison T DePewDepartment of Neuroscience, Vickie and Jack Farber Institute of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Lucas RestrepoDepartment of Neuroscience, Vickie and Jack Farber Institute of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Timothy J MoscaDepartment of Neuroscience, Vickie and Jack Farber Institute of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107 timothy.mosca@jefferson.edu.ORCID 0000-0003-3485-0719
Thomas Jefferson University · US

Funding

Molecular and cellular mechanisms that underlie synaptic maturationR01NS110907 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI MOSCA, TIMOTHY J. · 2019 to 2023
$2.1M
The Development and Organization of Central Synapses in DrosophilaR00DC013059 · NIDCD · THOMAS JEFFERSON UNIVERSITY · PI MOSCA, TIMOTHY J. · 2017 to 2019
$741k
NIDCD NIH HHS R00 DC013059NINDS NIH HHS R01 NS110907
6 · The paper itself

Abstract

Developing neurons must meet core molecular, cellular, and temporal requirements to ensure the correct formation of synapses, resulting in functional circuits. However, because of the vast diversity in neuronal class and function, it is unclear whether or not all neurons use the same organizational mechanisms to form synaptic connections and achieve functional and morphologic maturation. Moreover, it remains unknown whether neurons united in a common goal and comprising the same sensory circuit develop on similar timescales and use identical molecular approaches to ensure the formation of the correct number of synapses. To begin to answer these questions, we took advantage of the

Indexed as

Olfactory Receptor NeuronsAnimalsDrosophilaFemaleGlycogen Synthase Kinase 3 betaMaleOlfactory PathwaysSmellSynapsesGlycogen Synthase Kinase 3 betaantennal lobeCNSdevelopmentDrosophilaolfactionsynapse

Identifiers

PMID36446587
PMCPMC9838713
OpenAlexW4310358064

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.