Evidence map›Paper›PMID 36450281›Full record

ReviewAnnual review of medicine2023

Club Cell Secretory Protein in Lung Disease: Emerging Concepts and Potential Therapeutics.

Tereza Martinu, Jamie L Todd, Andrew E Gelman, Stefano Guerra, Scott M Palmer

Open access · hybridAbstract readReview
In one paragraph

Review in Annual review of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 55 citations in OpenAlex.

  1. Trial
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  13. Proteomic Characterization of HIV Infection.Advances in experimental medicine and biology · 2026
    Review
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  19. Effect of therapeutic hypothermia on surfactant proteins, anti-inflammatory and pro-fibrotic mediators.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Tereza MartinuDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada; email: tereza.martinu@uhn.ca.
Jamie L ToddDivision of Pulmonary, Allergy and Critical Care, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Andrew E GelmanDepartment of Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Stefano GuerraAsthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona, USA.
Scott M PalmerDivision of Pulmonary, Allergy and Critical Care, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Clinical Research Institute · USDuke University Hospital · USUniversity Health Network · CAUniversity of Arizona · USWashington University in St. Louis · US

Funding

The Role of Neutrophils in Regulating Lung Transplant ToleranceP01AI116501 · NIAID · WASHINGTON UNIVERSITY · PI ALEXANDER S. KRUPNICK · 2015 to 2026
$19.4M
Tollip inhibits IL-33 signaling during airway influenza virus infectionU19AI125357 · NIAID · UNIVERSITY OF ARIZONA · PI VOELKER, DENNIS R. · 2016 to 2025
$14.7M
THE ROLE OF ISCHEMIA REPERFUSION INJURY IN LUNG ALLOGRAFT REJECTIONR01HL094601 · NHLBI · WASHINGTON UNIVERSITY · PI Andrew Eric Gelman, Daniel Kreisel · 2009 to 2026
$6.9M
CC16 in Childhood and Resilience to Persistent Asthma into Adult Life (Supplement)R01AI135108 · NIAID · UNIVERSITY OF ARIZONA · PI Stefano Guerra · 2017 to 2026
$5.4M
NHLBI NIH HHS R01 HL094601NIAID NIH HHS P01 AI116501NIAID NIH HHS R01 AI135108NIAID NIH HHS U19 AI125357
6 · The paper itself

Abstract

Club cell secretory protein (CCSP), also known as secretoglobin 1A1 (gene name

Indexed as

Lung DiseasesHumansLungProteinsProteinsbiomarkerCC10CCSPclub cell secretory proteinlung biologySCGB1A1secretoglobin 1A1uteroglobin

Identifiers

PMID36450281
PMCPMC10472444
OpenAlexW4310470889

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.