ArticleInternational breastfeeding journal2022
Determinants of delayed onset of lactogenesis II among women who delivered via Cesarean section at a tertiary hospital in China: a prospective cohort study.
Article in International breastfeeding journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Mechanistic Pathways Underlying Breastfeeding Challenges Following Cesarean Delivery: A Systematic Review.Nutrients · 2026Pooled it
- Incidence and factors influencing delayed onset of lactation: a systematic review and meta-analysis.International breastfeeding journal · 2024Pooled it
- Efficacy and safety of acupuncture for postpartum hypogalactia: A systematic review and meta-analysis of randomized controlled trials.PloS one · 2024Pooled it
- Effects of hydromorphone-based patient-controlled intravenous analgesia on postpartum depression after cesarean section: a prospective randomized controlled trial.Frontiers in medicine · 2025Trial
- Effect of early essential newborn care on breastfeeding and outcomes of mothers/newborns post-cesarean section: a randomized controlled trial in China.Reproductive health · 2024Trial
- Decoding the HMO‒microbiome axis: bridging maternal milk to infant health outcomes.Gut microbes · 2026Review
- Impact of Press Needle Combining Breast Massage on Onset of Lactogenesis II in Post-Cesarean Mothers: A Randomized Controlled Trial.Chinese journal of integrative medicine · 2026Article
- Effect of a Culturally Based Intervention Model on Infant Weight and Maternal Perceptions of Breastfeeding Adequacy Following Caesarean Section: Quasi-Experimental Study.Asian/Pacific Island nursing journal · 2026Article
- Development and validation of a risk prediction model of delayed onset of lactogenesis among mothers with gestational diabetes mellitus: a prospective multicenter study.Frontiers in clinical diabetes and healthcare · 2026Article
- Effect of ropivacaine-dexamethasone combination on postpartum uterine pain, inflammation, and breastfeeding in multiparous women.American journal of translational research · 2026Article
- Factors influencing delayed lactogenesis II among advanced-age women following cesarean section: a retrospective analysis and predictive model development.Frontiers in medicine · 2026Article
- Knowledge, attitude, and practice toward delayed onset of lactogenesis among postpartum women experiencing mother-infant separation: a multi-center cross-sectional study.International breastfeeding journal · 2025Article
- Determinants of Breastfeeding Practices Pre- and During the COVID-19 Pandemic: A Retrospective Cohort Study.Healthcare (Basel, Switzerland) · 2025Article
- Development and validation of a model for predicting the risks for delayed onset of lactogenesis stage II for Chinese pregnant women.Scientific reports · 2025Article
- Breast milk NaScientific reports · 2025Article
- Consecutive Lactation, Infant Birth Weight and Sex Do Not Associate with Milk Production and Infant Milk Intake in Breastfeeding Women.Nutrients · 2025Article
- Review
- Timely initiation of breastfeeding and its associated factors among immediate postpartum mother-newborn pairs in Debre Tabor comprehensive specialized hospital, South Gondar Zone, North West, Ethiopia.BMC pregnancy and childbirth · 2024Article
- The Role of Skin-to-Skin Contact and Breastfeeding in the First Hour Post Delivery in Reducing Excessive Weight Loss.Children (Basel, Switzerland) · 2024Article
- Multisensory stimulation and its effect on breast milk volume production in mothers of premature infants.Frontiers in pediatrics · 2024Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCesarean birth is associated with a higher prevalence of delayed onset of lactogenesis II (DOLII) than vaginal birth. DOLII refers to the delayed initiation of copious milk production beyond 72 h after birth. This study aimed to determine the prevalence of, and factors associated with, DOLII among women who delivered via Cesarean section in China.
methodsThis prospective longitudinal cohort study recruited 468 women who delivered via Cesarean section at a tertiary hospital in China from 9 October 2021 to 17 May 2022. Face-to-face interviews were conducted during their delivery hospital stay to obtain information about demographic, medical, and breastfeeding factors. We assessed the onset of lactogenesis on postpartum day four, based on the maternal perception of changes in breast fullness. The Edinburgh Postnatal Depression Scale (EPDS) was used to screen for postpartum depression. Women with DOLII were interviewed via telephone or WeChat daily for one week postpartum to determine the timing of the onset of lactogenesis II. Univariate and multivariable logistic regression analyses were used to identify the determinants of DOLII.
resultsDOLII was experienced by 156 of 468 participants (33.3%). After adjusting for potential confounders, the odds of DOLII were 95% higher in primiparous women than multiparous women (adjusted odds ratio [aOR] 1.95; 95% confidence interval [CI] 1.29, 2.98), 75% higher in women with a serum albumin concentration < 35 g / L than women with normal serum albumin concentrations (aOR 1.78; 95% CI 1.09, 2.99), increased by 2.03-fold in women with an EPDS score ≥ 10 than women with an EPDS score < 10 (aOR 2.03; 95% CI 1.35, 3.07), and decreased in women with a higher number of breastfeeding sessions in the first 48 h postpartum (aOR 0.88; 95% CI 0.83, 0.93).
conclusionsOne-third of women with Cesarean section delivery experienced DOLII. DOLII was more likely in women who were primiparous, had a serum albumin concentration < 35 g / L, had a lower frequency of breastfeeding sessions, and had an EPDS score ≥ 10. Women with these risk factors who deliver via Cesarean section may need early breastfeeding support to ensure successful lactation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.