Evidence map›Paper›PMID 36451778›Full record

ArticleIBRO neuroscience reports2022

PlexinA1-deficient mice exhibit decreased cell density and augmented oxidative stress in parvalbumin-expressing interneurons in the medial prefrontal cortex.

Mst Sharifa Jahan, Takamasa Tsuzuki, Takuji Ito, Md Eliusur Rahman Bhuiyan, Ikuko Takahashi, Hyota Takamatsu, Atsushi Kumanogoh, Takayuki Negishi, Kazunori Yukawa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IBRO neuroscience reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mst Sharifa JahanDepartment of Physiology, Faculty of Pharmacy, Meijo University, Nagoya, Japan.
Takamasa TsuzukiDepartment of Physiology, Faculty of Pharmacy, Meijo University, Nagoya, Japan.
Takuji ItoDepartment of Physiology, Faculty of Pharmacy, Meijo University, Nagoya, Japan.
Md Eliusur Rahman BhuiyanDepartment of Physiology, Faculty of Pharmacy, Meijo University, Nagoya, Japan.
Ikuko TakahashiRadioisotope Center, Faculty of Pharmacy, Meijo University, Nagoya, Japan.
Hyota TakamatsuDepartment of Immunopathology, Immunology Frontier Research Center, Osaka University, Suita, Japan.
Atsushi KumanogohDepartment of Immunopathology, Immunology Frontier Research Center, Osaka University, Suita, Japan.
Takayuki NegishiDepartment of Physiology, Faculty of Pharmacy, Meijo University, Nagoya, Japan.
Kazunori YukawaDepartment of Physiology, Faculty of Pharmacy, Meijo University, Nagoya, Japan.
Meijo University · JPThe University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PlexinA1 (PlxnA1) is a transmembrane receptor for semaphorins (Semas), a large family of axonal guidance cues vital during neural development. PlxnA1 is expressed in embryonic interneurons, and

Indexed as

8-oxo-dG, 8 hydroxyguanineCR cells, calretinin-positive cellsGABAergic neuronsKO, knockoutMICAL1MICAL1, molecule interacting with CasL 1mPFC, medial prefrontal cortexOxidative stressParvalbumin-expressing interneuronsPlexinPlxnA1, PlexinA1PND, postnatal dayPNNs, perineuronal netsPrepulse inhibitionPV cells, parvalbumin-expressing interneuronsSchizophreniaSemaphorinSema, semaphorinSST cells, somatostatin-positive cellsWT, wild type mice

Identifiers

PMID36451778
PMCPMC9703010
OpenAlexW4308842037

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.