Evidence map›Paper›PMID 36452406›Full record

ArticleFrontiers in molecular neuroscience2022

PP2A phosphatase regulates cell-type specific cytoskeletal organization to drive dendrite diversity.

Shatabdi Bhattacharjee, Erin N Lottes, Sumit Nanda, Andre Golshir, Atit A Patel, Giorgio A Ascoli, Daniel N Cox

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shatabdi BhattacharjeeNeuroscience Institute, Georgia State University, Atlanta, GA, United States.
Erin N LottesNeuroscience Institute, Georgia State University, Atlanta, GA, United States.
Sumit NandaCenter for Neural Informatics, Structures, and Plasticity, Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA, United States.
Andre GolshirNeuroscience Institute, Georgia State University, Atlanta, GA, United States.
Atit A PatelNeuroscience Institute, Georgia State University, Atlanta, GA, United States.
Giorgio A AscoliCenter for Neural Informatics, Structures, and Plasticity, Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA, United States.
Daniel N CoxNeuroscience Institute, Georgia State University, Atlanta, GA, United States.
Georgia State University · USGeorge Mason University · USInstitute for Advanced Study · US

Funding

Generation and Description of Neuronal Morphology and ConnectivityR01NS039600 · NINDS · GEORGE MASON UNIVERSITY · PI ASCOLI, GIORGIO A · 1999 to 2024
$6.9M
Cytoskeletal mechanisms of dendrite arbor shape developmentR01NS086082 · NINDS · GEORGIA STATE UNIVERSITY · PI ASCOLI, GIORGIO A, COX, DANIEL N · 2013 to 2023
$3.1M
NINDS NIH HHS R01 NS039600NINDS NIH HHS R01 NS086082
6 · The paper itself

Abstract

Uncovering molecular mechanisms regulating dendritic diversification is essential to understanding the formation and modulation of functional neural circuitry. Transcription factors play critical roles in promoting dendritic diversity and here, we identify PP2A phosphatase function as a downstream effector of Cut-mediated transcriptional regulation of dendrite development. Mutant analyses of the PP2A catalytic subunit (

Indexed as

cytoskeletondendriteDrosophilamicrotubulesneuronal polarityprotein phosphatase 2Atranscriptional regulation

Identifiers

PMID36452406
PMCPMC9702092
OpenAlexW4309043023

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.