Evidence map›Paper›PMID 36453897›Full record

ArticleMicrobiology spectrum2022

ISG15 Is a Novel Regulator of Lipid Metabolism during

Manuel Albert, Jesús Vázquez, Juan M Falcón-Pérez, María A Balboa, Marc Liesa, Jesús Balsinde, Susana Guerra

Abstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  9. Article
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  11. Article
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  14. HIV Infection Drives Foam Cell Formation via NLRP3 Inflammasome Activation.International journal of molecular sciences · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Glycerol monolaurate inhibitsmicroPublication biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manuel AlbertDepartment of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0000-0001-9774-3668
Jesús VázquezCentro Nacional de Investigaciones Cardiovasculares (CNIC-ISCIII), Madrid, Spain.
Juan M Falcón-PérezCIC-bioGUNE-Centro de Investigación Cooperativa en Biociencias, Vizcaya, Spain.
María A BalboaConsejo Superior de Investigaciones Científicas (CSIC), Instituto de Biología y Genética Molecular, Valladolid, Spain.
Marc LiesaDepartment of Medicine, Endocrinology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Jesús BalsindeConsejo Superior de Investigaciones Científicas (CSIC), Instituto de Biología y Genética Molecular, Valladolid, Spain.
Susana GuerraDepartment of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0000-0001-9067-2991

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferon-stimulated gene 15 (ISG15) is a 15-kDa ubiquitin-like modifier that binds to target proteins in a process termed ISGylation. ISG15, first described as an antiviral molecule against many viruses, participates in numerous cellular processes, from immune modulation to the regulation of genome stability. Interestingly, the role of ISG15 as a regulator of cell metabolism has recently gained strength. We previously described ISG15 as a regulator of mitochondrial functions in bone marrow-derived macrophages (BMDMs) in the context of

Indexed as

CytokinesLipid MetabolismUbiquitinsVacciniaAnimalsInterferonsLipidsPPAR gammaVaccinia virusCytokinesInterferonsLipidsPPAR gammaUbiquitinshost-pathogen interactionsinnate immunityinterferons

Identifiers

PMID36453897
PMCPMC9769738

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.