ArticleUnited European gastroenterology journal2023
Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.
Article in United European gastroenterology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- Computed Tomography and Plasma Proteomics for Early Discrimination of Post-Pancreatitis Diabetes Mellitus.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Burden of non-cancer comorbidities and mortality in chronic pancreatitis: a retrospective cohort study.BMJ open gastroenterology · 2026Article
- An interpretable radiomics model based on contrast‑enhanced pancreatic computed tomography for predicting the prognosis of post-acute pancreatitis diabetes mellitus.BMC medical imaging · 2026Article
- Early mechanisms of diabetes development in pediatric pancreatitis: A pilot study.Journal of pediatric gastroenterology and nutrition · 2026Article
- Chronic pancreatitis and pancreatogenic type 3c diabetes risk: a systematic review and meta-analysis.Therapeutic advances in endocrinology and metabolism · 2026Article
- Etiology, diagnosis, and management of chronic pancreatitis associated primary complications: a narrative review.Frontiers in medicine · 2026Review
- Pancreatogenic diabetes: Pathophysiology, diagnosis, and management challenges.World journal of gastrointestinal surgery · 2025Review
- Glucose metabolism after distal pancreatectomy - deterioration of beta cell function becomes noticeable at an early stage: a retrospective cohort study.BMC surgery · 2025Article
- Risk Factors and Mechanisms for Diabetes in Pancreatitis.Gastroenterology clinics of North America · 2025Review
- Treatment outcomes with oral anti-hyperglycaemic therapies in people with diabetes secondary to a pancreatic condition (type 3c diabetes): A population-based cohort study.Diabetes, obesity & metabolism · 2025Article
- Groove Pancreatitis in Focus: Tumor-Mimicking Phenotype, Diagnosis, and Management Insights.Journal of clinical medicine · 2025Article
- Six-fold increased risk of acute pancreatitis in alcohol-related liver disease compared to matched comparators: A population-based cohort study.Journal of internal medicine · 2025Article
- Type 5 diabetes mellitus: redefining pancreatogenic diabetes through molecular, imaging, and AI-driven evidence.Frontiers in endocrinology · 2025Review
- Transcriptomic analysis reveals the crosstalk between type 2 diabetes and chronic pancreatitis.Health science reports · 2024Article
- A radiomics model of contrast-enhanced computed tomography for predicting post-acute pancreatitis diabetes mellitus.Quantitative imaging in medicine and surgery · 2024Article
- Comments on Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes: Authors' reply.United European gastroenterology journal · 2023Article
- Comments on Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.United European gastroenterology journal · 2023Article
- Post-pancreatitis diabetes mellitus is common in chronic pancreatitis and is associated with adverse outcomes.United European gastroenterology journal · 2023Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPost-pancreatitis diabetes mellitus (PPDM) is a common consequence of chronic pancreatitis (CP). We aimed to determine the incidence and predictors of PPDM after CP onset, as well as complications and antidiabetic therapy requirements, in a high-volume tertiary center.
methodsWe did a cohort study with retrospectively collected data from patients with definite CP seen at the Karolinska University Hospital between January 1999 and December 2020. Cause-specific Cox regression analysis was used to assess PPDM predictors. To estimate risk of complications and need for therapy the Fine-Gray subdistribution hazard model was employed, accounting for death as a competing risk.
resultsWe identified 481 patients with CP. The cumulative incidence of PPDM was 5.1%, 13.2%, 27.5% and 38.9% at 5, 10, 15 and 20 years, respectively. Compared to CP patients without diabetes, patients with PPDM were predominantly male (55% vs. 75%), had more frequently alcoholic etiology (44% vs. 62%) and previous acute pancreatitis. The only independent predictor of PPDM was presence of pancreatic calcifications (aHR = 2.45, 95% CI 1.30-4.63). Patients with PPDM had higher rates of microangiopathy (aSHR = 1.59, 95% CI 1.02-2.52) and infection (aSHR = 4.53, 95% CI 2.60-9.09) compared to CP patients who had type 2 diabetes (T2DM). The rate of insulin use was three-fold higher, whereas metformin use rate was two-fold higher in the same comparison.
conclusionsPatients with PPDM have a higher frequency of clinically significant complications and were more commonly prescribed insulin and metformin, suggesting a more aggressive phenotype than that of T2DM. Greater PPDM awareness is needed to optimize disease management.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.