Evidence map›Paper›PMID 36454189›Full record

Trial reportThe International journal of eating disorders2023

Predictors of family-based treatment for adolescent eating disorders: Do family or diagnostic factors matter?

Nandini Datta, Kelsey Hagan, Cara Bohon, May Stern, Bohye Kim, Brittany E Matheson, Sasha Gorrell, Daniel Le Grange, James D Lock

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The International journal of eating disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Observational
  5. Review
  6. Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Nandini DattaDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0001-6109-7385
Kelsey HaganDepartment of Psychiatry, New York State Psychiatric Institute, Columbia University Irving Medical Center, New York, New York, USA.
Cara BohonDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
May SternDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
Bohye KimDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
Brittany E MathesonDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0001-8607-5019
Sasha GorrellDepartment of Psychiatry & Behavioral Sciences, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-8861-8547
Daniel Le GrangeDepartment of Psychiatry & Behavioral Sciences, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0001-7293-9496
James D LockDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-5169-1484
Stanford University · USUniversity of California, San Francisco · USColumbia University · USStructural Analytics (United States) · US

Funding

Confirming the Efficacy/Mechanism of an Adaptive Treatment for Adolescent Anorexia NervosaR01MH110538 · NIMH · STANFORD UNIVERSITY · PI LOCK, JAMES D · 2017 to 2021
$3.8M
Treatment of Adolescents with Anorexia NervosaR01MH070621 · NIMH · STANFORD UNIVERSITY · PI LOCK, JAMES D · 2004 to 2008
$2.0M
UCSD Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Faculty Development ProgramR25NS117367 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Victoria B Risbrough, Joann Trejo · 2020 to 2026
$1.6M
2/2-Treatment of Adolescent BulimicsR01MH079979 · NIMH · UNIVERSITY OF CHICAGO · PI LE GRANGE, DANIEL · 2008 to 2012
$1.5M
Family Therapy in the Treatment of Adolescent Anorexia NervosaU01MH076290 · NIMH · STANFORD UNIVERSITY · PI AGRAS, WILLIAM STEWART · 2006 to 2010
$1.4M
Treatment for Adolescent Anorexia NervosaR01MH070620 · NIMH · UNIVERSITY OF CHICAGO · PI LE GRANGE, DANIEL · 2004 to 2008
$1.4M
Neural Correlates of Reinforcement Learning Specific to Hyperactivityin Adolescent Anorexia NervosaK23MH126201 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORRELL, SASHA CATHERINE · 2021 to 2025
$848k
Cognitive Remediation Therapy for Anorexia NervosaR01MH082706 · NIMH · STANFORD UNIVERSITY · PI LOCK, JAMES D · 2007 to 2009
$711k
2/2-Adaptive Family Treatment for Adolescent Anorexia NervosaR34MH093493 · NIMH · STANFORD UNIVERSITY · PI LOCK, JAMES D · 2011 to 2013
$710k
1/2-Adaptive Family Treatment for Adolescent AnorexiaR34MH093768 · NIMH · UNIVERSITY OF CHICAGO · PI LE GRANGE, DANIEL · 2011 to 2013
$709k
Feasibility of Combining Family and Cognitive Therapy to Prevent Chronic AnorexiaR34MH101281 · NIMH · STANFORD UNIVERSITY · PI LOCK, JAMES D · 2013 to 2015
$707k
NIMH NIH HHS K23 MH126201NIMH NIH HHS R01 MH070620NIMH NIH HHS R01 MH070621NIMH NIH HHS R01 MH079979NIMH NIH HHS R01 MH082706NIMH NIH HHS R01 MH110538NIMH NIH HHS R34 MH093493NIMH NIH HHS R34 MH093768NIMH NIH HHS R34 MH101281NIMH NIH HHS U01 MH076290NINDS NIH HHS R25 NS117367
6 · The paper itself

Abstract

objectiveMisconceptions around which patients will and will not benefit from family-based treatment (FBT) for adolescent eating disorders (EDs) limit referrals and access to this treatment modality. The present study explored whether common demographic and clinical factors that may prevent referral to FBT predict treatment outcomes in adolescent anorexia nervosa (AN) and bulimia nervosa (BN).

methodThe following predictors of treatment outcomes were assessed: baseline family and diagnostic factors (socioeconomic status, comorbidity, illness duration, parent feelings of self-efficacy, family status, prior treatment, sex and prior hospitalizations) in a combined sample of adolescents receiving FBT compared to those randomized to other treatment conditions, across six clinical trials in the United States and Canada (total n = 724, ages 12-18, 90% female across both diagnoses). AN and BN samples were examined separately.

resultsAny prior ED treatment emerged as the only predictor of outcome in AN and BN, such that having no prior treatment predicted better outcomes in FBT for AN, and in both FBT and other treatment modalities for BN. No other sociodemographic or clinical variables predicted outcomes for AN or BN in FBT or in other evidence-based treatment modalities.

conclusionsThe findings of this exploratory analysis suggest that commonly assumed factors do not predict outcome in FBT. Specifically socioeconomic and demographic factors or clinical variability in families seeking treatment do not predict treatment outcomes in FBT, or other evidence-based treatment modalities, with the exception of prior treatment. Providers should consider referring to FBT even when these factors are present. PUBLIC SIGNIFICANCE: This manuscript reports that commonly assumed family, sociodemographic and diagnostic factors do not predict outcome in FBT or other evidence-based treatment modalities, with the exception of prior treatment. This data may be helpful for providers when considering referrals to FBT in the context of variability in these variables.

Indexed as

Anorexia NervosaBulimia NervosaFamily TherapyAdolescentChildFemaleHumansMaleParentsSocioeconomic FactorsTreatment Outcomeadolescentanorexia nervosabulimia nervosafamily-based treatmentpredictors

Identifiers

PMID36454189
PMCPMC9898138
OpenAlexW4310497335

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.