Evidence map›Paper›PMID 36454458›Full record

ArticleAdvances in experimental medicine and biology2023

Genome Editing and Cardiac Regeneration.

Rayhaan Bassawon, Kashif Khan, Ateeque Siddique, Dominique Shum-Tim

Abstract read
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In one paragraph

Article in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rayhaan BassawonDivision of Cardiac Surgery, Royal Victoria Hospital, McGill University Health Centre, Montreal, QC, Canada.
Kashif KhanDivision of Cardiology and Cardiac Surgery, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.
Ateeque SiddiqueDivision of Cardiology and Cardiac Surgery, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.
Dominique Shum-TimDivision of Cardiac Surgery, Royal Victoria Hospital, McGill University Health Centre, Montreal, QC, Canada. dshumtim@yahoo.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the field of cardiac regeneration is relatively young, it is progressing rapidly with technological advancements. Genome editing tools are allowing researchers to creatively influence signaling pathways to be able to shed light on them and are important for addressing certain issues and limitations associated with in vitro and in vivo aspects of cardiac regeneration, such as imaging and immune rejection. In this chapter, the pathways involved in cardiac regeneration will be highlighted, and the role of gene-editing tools in endogenous and exogenous approaches to regenerate injured myocardium is discussed.

Indexed as

Gene EditingHeartHumansMyocardiumResearch PersonnelAdeno-associated virusCardiomyocytesCRISPR/Cas9iPSCsIschemic heart disease

Identifiers

PMID36454458

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.