Evidence map›Paper›PMID 36457554›Full record

ReviewFrontiers in endocrinology2022

A review of the hormones involved in the endocrine dysfunctions of polycystic ovary syndrome and their interactions.

Rebecca H K Emanuel, Josh Roberts, Paul D Docherty, Helen Lunt, Rebecca E Campbell, Knut Möller

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  14. The Ovary-Liver Axis: Molecular Science and Epidemiology.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rebecca H K EmanuelDepartment of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand.
Josh RobertsDepartment of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand.
Paul D DochertyDepartment of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand.
Helen LuntDiabetes Services, Te Whatu Ora Waitaha Canterbury, Canterbury, New Zealand.
Rebecca E CampbellSchool of Biomedical Sciences, Department of Physiology, Centre for Neuroendocrinology, University of Otago, Dunedin, New Zealand.
Knut MöllerInstitute of Technical Medicine, Furtwangen University, Villingen-Schwenningen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) affects up to 20% of women but remains poorly understood. It is a heterogeneous condition with many potential comorbidities. This review offers an overview of the dysregulation of the reproductive and metabolic systems associated with PCOS. Review of the literature informed the development of a comprehensive summarizing 'wiring' diagram of PCOS-related features. This review provides a justification for each diagram aspect from the relevant academic literature, and explores the interactions between the hypothalamus, ovarian follicles, adipose tissue, reproductive hormones and other organ systems. The diagram will provide an efficient and useful tool for those researching and treating PCOS to understand the current state of knowledge on the complexity and variability of PCOS.

Indexed as

Polycystic Ovary SyndromeAdipose TissueFemaleHormonesHumansOvarian FollicleReproductionHormonesendocrinehormonesmetabolicPCOSreproductive

Identifiers

PMID36457554
PMCPMC9705998

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.