Evidence map›Paper›PMID 36459393›Full record

SynthesisJMIR public health and surveillance2022

The Practice and Potential Role of HIV Self-testing in China: Systematic Review and Meta-analysis.

Xiangfei Xiu, Yuanyuan Qin, Yugang Bao, Yaokai Chen, Hao Wu, Xiaojie Huang, Lu Wang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in JMIR public health and surveillance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiangfei XiuNational Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.ORCID 0000-0002-5049-725X
Yuanyuan QinClinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-0482-4632
Yugang BaoAIDS Healthcare Foundation, Beijing, China.ORCID 0000-0002-7291-0009
Yaokai ChenDivision of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, China.ORCID 0000-0002-3229-0108
Hao WuClinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-7096-2027
Xiaojie Huang *Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-5045-9202
Lu Wang *National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.ORCID 0000-0002-6701-9676

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV self-testing (HIVST) is recommended by the World Health Organization as a valid approach to routine HIV testing services. The scale of HIVST use has gradually been expanded in China over the past 5 years. To take a closer look at the role of HIVST in China, we reviewed the promotion and application of HIVST within China.

objectiveThe main objective of this study was to systematically analyze the proportion of past use and actual uptake of HIVST within China. Moreover, we aimed to quantify the effect of HIVST on HIV prevention and treatment.

methodsIn all, 5 medical databases and 2 registration systems, including PubMed, Web of Science, MEDLINE, WanFang, China National Knowledge Internet, ClinicalTrials.gov, and the Chinese Clinical Trial Registry were systematically searched for studies reporting the prevalence of HIVST use from January 1, 2010, to December 25, 2021. Meta-analyses of the pooled proportion estimates were carried out by the meta-package in R software (version 4.1.2). Statistical heterogeneity among the studies was estimated using Cochran Q test and the inconsistency index (I

resultsA total of 50 studies were included in our systematic review. The estimated pooled prevalence of HIVST use in China was 29.9% (95% CI 22.5%-37.9%). Among individuals who have ever used HIVST, 47.5% (95% CI 37.2%-57.8%) were tested for HIV for the first time. The pooled reactive rate of HIVST was 4.2% (95% CI 3.1%-5.8%). When HIVST revealed a reactive result, 81.3% (95% CI 70.9%-91.6%) of individuals sought medical care.

conclusionsIn recent times, HIVST has become a valuable tool for HIV prevention in China. The widespread use of HIVST in non-men who have sex with men populations needs to be endorsed and promoted. The long-term applications of HIVST and the potential consequences of self-financing of HIVST in China have yet to be explored.

trial registrationPROSPERO CRD42022304846; https://tinyurl.com/54d9pxy8.

Indexed as

HIV InfectionsSelf-TestingChinaHIV TestingHumansInternetChinaHIVmeta-analysisprevalenceself-testing

Identifiers

PMID36459393
PMCPMC9758640

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.