Evidence map›Paper›PMID 36460990›Full record

ArticleBMC infectious diseases2022

Non-falciparum species and submicroscopic infections in three epidemiological malaria facets in Cameroon.

Loick Pradel Kojom Foko, Joseph Hawadak, Francine Dorgelesse Kouemo Motse, Carole Else Eboumbou Moukoko, Lugarde Kamgain Mawabo, Veena Pande, Vineeta Singh

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Complex non-Research square · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. NovelAntimicrobial agents and chemotherapy · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Phytofabrication and characterization ofFrontiers in bioengineering and biotechnology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Loick Pradel Kojom FokoICMR-National Institute of Malaria Research, Dwarka, New-Delhi, 110077, India.
Joseph HawadakICMR-National Institute of Malaria Research, Dwarka, New-Delhi, 110077, India.
Francine Dorgelesse Kouemo MotseDepartment of Medical Laboratory Sciences, Faculty of Health Sciences, University of Buea, 63, Buea, Cameroon.
Carole Else Eboumbou MoukokoDepartment of Biological Sciences, Faculty of Medicine and Pharmaceutical Sciences, The University of Douala, 24157, Douala, Cameroon.
Lugarde Kamgain MawaboLaboratoire Sainte Therese, Douala, Cameroon.
Veena PandeDepartment of Biotechnology, Kumaun University, Bhimtal, Uttarakhand, 263001, India.
Vineeta SinghICMR-National Institute of Malaria Research, Dwarka, New-Delhi, 110077, India. vineetas_2000@yahoo.com.
Kumaun University · INCentre Pasteur du Cameroun · CMNational Institute of Malaria Research · INUniversity of Buea · CMUniversity of Douala · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are growing reports on the prevalence of non-falciparum species and submicroscopic infections in sub-Saharan African countries but little information is available from Cameroon.

methodsA hospital-based cross-sectional study was carried out in four towns (Douala, Maroua, Mayo-Oulo, and Pette) from three malaria epidemiological strata (Forest, Sahelian, and Soudanian) of Cameroon. Malaria parasites were detected by Giemsa light microscopy and polymerase chain reaction (PCR) assay. Non-falciparum isolates were characterized and their 18S gene sequences were BLASTed for confirmatory diagnosis.

resultsPCR assay detected malaria parasites in 82.4% (98/119) patients, among them 12.2% (12/98) were asymptomatic cases. Three Plasmodium species viz. P. falciparum, P. ovale curtisi and P. vivax, and two co-infection types (P. falciparum + P. vivax and P. falciparum + P. ovale curtisi) were found. The remaining infections were mono-infections with either P. falciparum or P. ovale curtisi. All non-falciparum infections were symptomatic and microscopic. The overall proportion of submicroscopic infections was 11.8% (14/119). Most asymptomatic and submicroscopic infection cases were self-medicated with antimalarial drugs and/or medicinal plants. On analysis, P. ovale curtisi sequences were found to be phylogenetically closer to sequences from India while P. vivax isolates appeared closer to those from Nigeria, India, and Cameroon. No G6PD-d case was found among non-falciparum infections.

conclusionsThis study confirms our previous work on circulation of P. vivax and P. ovale curtisi and the absence of P. knowlesi in Cameroon. More studies are needed to address non-falciparum malaria along with submicroscopic infections for effective malaria management and control in Cameroon.

Indexed as

AntimalarialsMalariaMalaria, FalciparumMalaria, VivaxCameroonCross-Sectional StudiesHumansAntimalarialsCameroonMalariaNon-falciparum speciesSubmicroscopic infections

Identifiers

PMID36460990
PMCPMC9718470
OpenAlexW4311125934

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.