Evidence map›Paper›PMID 36465851›Full record

ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2022

Mechanism of action of

Salah Abdulrazak Alshehade, Raghdaa Hamdan Al Zarzour, Vikneswaran Murugaiyah, Sharoen Yu Ming Lim, Huda Ghaleb El-Refae, Mohammed Abdullah Alshawsh

Open access · hybridAbstract read
In one paragraph

Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Pharmaceuticals (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Salah Abdulrazak AlshehadeDepartment of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang 11800, Malaysia.
Raghdaa Hamdan Al ZarzourDepartment of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang 11800, Malaysia.
Vikneswaran MurugaiyahDepartment of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang 11800, Malaysia.
Sharoen Yu Ming LimDivision of Biomedical Sciences, School of Pharmacy, University of Nottingham Malaysia, Semenyih 43500, Malaysia.
Huda Ghaleb El-RefaeCollege of Pharmacy, Al Ain University, Al Ain 64141, United Arab Emirates.
Mohammed Abdullah AlshawshDepartment of Pharmacology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Universiti Sains Malaysia · MYAl Ain University · AEUniversity of Malaya · MYUniversity of Nottingham Malaysia Campus · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is one of the most common complications of a metabolic syndrome caused by excessive accumulation of fat in the liver.

methodsThe effects of an ethanolic extract of

resultsA total of 27 bioactive compounds corresponding to 50 potential NAFLD-related targets were identified.

conclusionUsing the computational systems pharmacology approach, the potentially beneficial effect of

Indexed as

Cellular targetInflammationMedicinal plantMolecular dockingNon-alcoholic fatty liver diseaseOrthosiphon aristatusOrthosiphon stamineusOxidative stressPathway enrichment analysisProtein–protein interactionSystems pharmacology

Identifiers

PMID36465851
PMCPMC9715956
OpenAlexW4295664333

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.