Evidence map›Paper›PMID 36466099›Full record

ReviewEuroasian journal of hepato-gastroenterology2022

Gender Differences in Nonalcoholic Fatty Liver Disease.

Aabha Nagral, Manisha Bangar, Sherna Menezes, Shobna Bhatia, Nazish Butt, Jhumur Ghosh, Jayani Harshika Manchanayake, Mamun Al Mahtab, Shivaram Prasad Singh

Open access · diamondAbstract readReview
In one paragraph

Review in Euroasian journal of hepato-gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Sexual Dimorphism in the Development of Cardiometabolic Syndrome.Handbook of experimental pharmacology · 2026
    Review
  11. Article
  12. Article
  13. Interaction Between Photoperiod and Sex on Hepatic Lipid Homeostasis in Rats Fed an Obesogenic Diet.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Aabha NagralDepartment of Gastroenterology, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India; Apollo Hospital, Navi Mumbai, Maharashtra, India.ORCID https://orcid.org/0000-0003-0005-2508
Manisha BangarDivision of Gastroenterology and Hepatology, Century Hospitals, Hyderabad, Telangana, India.
Sherna MenezesDepartment of Gastroenterology, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.ORCID https://orcid.org/0000-0002-3230-3300
Shobna BhatiaDepartment of Gastroenterology, Sir HN Reliance Foundation Hospital, Mumbai, Maharashtra, India.
Nazish ButtDepartment of Gastroenterology, Jinnah Postgraduate Medical Center, Karachi, Pakistan.
Jhumur GhoshDepartment of Hepatology, MH Samorita Hospital and Medical College, Dhaka, Bangladesh.
Jayani Harshika ManchanayakeDepartment of Gastroenterology, National Hospital Colombo, Colombo, Sri Lanka.
Mamun Al MahtabDepartment of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.ORCID https://orcid.org/0000-0003-3728-3879
Shivaram Prasad SinghDepartment of Gastroenterology, SCB Medical College, Cuttack, Odisha, India.
Bangladesh Medical University · BDJinnah Postgraduate Medical Center · PKSir H.N. Reliance Foundation Hospital and Research Centre · INCARE Hospitals · INJaslok Hospital · INSriram Chandra Bhanja Medical College Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) has currently emerged as the most common liver disorder in both developed and developing countries. It has been observed that NAFLD exhibits sexual dimorphism, and there is limited understanding on the sex differences in adults with NAFLD. Nonalcoholic fatty liver disease shows marked differences in prevalence and severity with regards to gender. There are considerable biological disparities between males and females attributed to differences in the chromosomal makeup and sex hormone levels, distinct from the gender differences resulting from the sociocultural influences that lead to differences in lifestyle, which have a significant impact on the pathogenesis of this complex disorder. A multitude of factors contributes to the gender disparities seen and need to be researched in-depth to better understand the mechanisms behind them and the therapeutic measures that can be taken. In this article, we will review the gender disparities seen in NAFLD, as well as recent studies highlighting certain gender-specific factors contributing to its varying prevalence and severity. How to cite this article: Nagral A, Bangar M, Menezes S,

Indexed as

FibrosisGenderGender differenceLiver cancerMenopauseMetabolic syndromeMolecular pathogenesisNonalcoholic steatohepatitisPrevalenceSex hormones

Identifiers

PMID36466099
PMCPMC9681575
OpenAlexW4297830819

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.