Evidence mapPaperPMID 36466660Full record

ReviewFrontiers in microbiology2022

Metabolites extracted from microorganisms as potential inhibitors of glycosidases (α-glucosidase and α-amylase): A review.

Xiaojing Wang, Jiaying Li, Jiaqi Shang, Jing Bai, Kai Wu, Jing Liu, Zhijun Yang, Hao Ou, Lei Shao

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  3. Review
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  9. Review
  10. Review
  11. New Dibenzo-Marine drugs · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Xiaojing WangAffiliated Zhoupu Hospital, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Jiaying LiShanghai University of Medicine and Health Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jiaqi ShangSchool of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Jing BaiSchool of Chemistry and Life Sciences, Suzhou University of Science and Technology, Suzhou, China.
Kai WuSchool of Pharmacy, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Jing LiuSchool of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Zhijun YangSchool of Pharmacy, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Hao OuDepartment of Critical Care Medicine, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Lei ShaoSchool of Pharmacy, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Shanghai University of Medicine and Health Sciences · CNSuzhou University of Science and Technology · CNThird Xiangya Hospital · CNUniversity of Shanghai for Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α-Glucosidase and α-amylase are the two main glycosidases that participate in the metabolism of carbohydrates. Inhibitors of these two enzymes are considered an important medical treatment for carbohydrate uptake disorders, such as diabetes and obesity. Microbes are an important source of constituents that have the potential to inhibit glycosidases and can be used as sources of new drugs and dietary supplements. For example, the α-glucosidase inhibitor acarbose, isolated from

Indexed as

endophytesmarine microorganismmedical applicationmicrobesα-amylase inhibitorα-glucosidase inhibitor

Identifiers

PMID36466660
PMCPMC9712454
OpenAlexW4309609210

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.