Evidence map›Paper›PMID 36467694›Full record

ArticleFrontiers in physiology2022

Mechano-growth factor E-domain modulates cardiac contractile function through 14-3-3 protein interactomes.

Christopher Solís, Walter C Thompson, James R Peña, Christopher McDermott-Roe, Paulina Langa, Chad M Warren, Magdalena Chrzanowska, Beata M Wolska, R John Solaro, Pieter Detombe and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Mechanochemical coupling of MGF mediates periodontal regeneration.Bioengineering & translational medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Christopher SolísDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, United States.
Walter C ThompsonDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, United States.
James R PeñaDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI, United States.
Christopher McDermott-RoeDepartment of Medicine, and Department of Genetics, Perelman School of Medicine, Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, United States.
Paulina LangaDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, United States.
Chad M WarrenDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, United States.
Magdalena ChrzanowskaBlood Research Institute, Versiti, Department of Pharmacology and Toxicology, Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, United States.
Beata M WolskaCenter for Cardiovascular Research, University of Illinois at Chicago, Chicago, IL, United States.
R John SolaroDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, United States.
Pieter DetombeDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, United States.
Paul H GoldspinkDepartment of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL, United States.
University of Illinois Chicago · USMedical College of Wisconsin · USInserm · FRUniversity of Pennsylvania · USVersiti Blood Center of Wisconsin · US

Funding

Signaling To and From the Vascular/Endothelial Compartment and Progression of HCM Linked to Sarcomere MutationsR01HL158634 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GOLDSPINK, PAUL H, SOLARO, R JOHN · 2022 to 2025
$3.1M
Endothelial Rap1 in the control of heart functionR01HL157893 · NHLBI · VERSITI WISCONSIN, INC. · PI CHRZANOWSKA, MAGDALENA, GOLDSPINK, PAUL H · 2022 to 2025
$2.9M
NHLBI NIH HHS R01 HL157893NHLBI NIH HHS R01 HL158634
6 · The paper itself

Abstract

In the heart, alternative splicing of the

Indexed as

14-3-3 proteincontractile function of the heartE-domain peptidemechano-growth factorprotein-protein interaction (PPI)

Identifiers

PMID36467694
PMCPMC9709209
OpenAlexW4309312628

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.